Pulsed Laser Biosignal Detection for Low-Noise Analyte Measurement

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Solution Overview

Problem

Existing methods for noninvasive measurement of blood analytes face challenges with increased data complexity and noise interference from environmental light sources, affecting calculation accuracy.

Innovation Solution

A biological information detection device using a pulsed laser beam oscillated at a constant cycle, with a control unit to cut out detected signals as time segment data, allowing for noninvasive measurement of target substances with reduced noise.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If noninvasive measurement methods using multiple input variables are used to estimate blood analyte concentration, then measurement accessibility is improved, but data complexity increases

Engineering Contradiction:
Improvemeasurement accessibilityVSAvoiddata complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The patent extracts and removes environmental light components from the detected signal through signal processing. By separating the environmental light noise from the actual measurement signal, the system maintains noninvasive measurement capability while reducing data complexity and improving measurement accuracy

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs periodic modulation of the laser beam at a specific frequency and performs synchronous detection at that frequency. This periodic action allows the system to distinguish the modulated measurement signal from environmental light noise, thereby simplifying data processing while maintaining measurement accessibility

Inventive Principle:
Principle #19Periodic action

2Loss of information

If continuous monitoring of patient conditions is performed to improve real-time data collection, then information completeness is improved, but data processing burden increases

Engineering Contradiction:
Improveinformation completenessVSAvoiddata processing burden
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The patent uses periodic laser modulation and synchronous detection to continuously monitor blood analyte concentrations in real-time. The periodic sampling at a defined frequency enables continuous information collection while reducing the overall data processing burden through efficient signal extraction

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The patent implements continuous monitoring with real-time feedback of blood analyte concentration levels. The system continuously adjusts and processes signals to maintain accurate real-time information while managing data processing through efficient signal extraction and environmental noise removal

Inventive Principle:
Principle #23Feedback

3Adaptability or versatility

If environmental light is present during noninvasive measurement, then measurement coverage is improved, but measurement precision deteriorates due to noise

Engineering Contradiction:
Improvemeasurement coverageVSAvoidcalculation accuracy
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The patent modulates the laser beam periodically at a specific frequency and performs synchronous detection at that frequency. This allows the system to operate in environments with ambient light while maintaining measurement precision by selectively detecting only the modulated signal component

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The patent extracts and removes environmental light components from the detected signal through signal processing techniques. By separating the environmental noise from the measurement signal, the system maintains both wide measurement coverage and high calculation accuracy

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables accurate, noninvasive measurement of target substances in liquid biological objects with low noise levels, reducing data complexity and improving calculation precision.

Implementation Method 1

a laser oscillator that oscillates a pulsed laser beam oscillated at a suitable wavelength associated with a measuring target substance

Methodology Applied
Scientific EffectLight absorption: Absorption (EM radiation)

Data Source

PatentUS12474259B2Biological information detection device and biological information detection method
Publication Date: 2025.11.18 FUJITA MEDICAL INSTR CO LTD
  • US12474259B2 patent drawing
  • US12474259B2 patent drawing
  • US12474259B2 patent drawing

AI summary

The present invention is a biological information detection device including: a laser oscillator that oscillates a pulsed laser beam oscillated at a suitable wavelength associated with a measuring target substance; an irradiation mechanism that emits the pulsed laser beam to a liquid biological object inside which the measuring target substance exists; a light receiving sensor that receives a detected laser beam output from the liquid biological object; and a control unit that controls operations of respective components. The control unit outputs an oscillation instruction to the laser oscillator so as to oscillate the pulsed laser beam at a constant cycle, cuts out a detected signal received from the light receiving sensor as time segment data for a time period corresponding to the constant cycle, and calculates a quantity of the measuring target substance in the liquid biological object based on the time segment data.