Pulsed Laser Blood Analyte Detection With Time-Segment Noise Filtering

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Solution Overview

Problem

Conventional methods for noninvasive measurement of blood analytes, such as lactic acid, face challenges with increased data complexity and noise interference from external light sources, leading to reduced calculation accuracy.

Innovation Solution

A biological information detection device using a pulsed laser beam oscillated at a constant cycle, with a wavelength of 1480 nm, to measure lactic acid in a liquid biological object by cutting out detected signals as time segment data, reducing noise and improving accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If conventional noninvasive measurement methods are used to measure blood analytes, then measurement can be performed without invasive sample collection, but the measurement precision is reduced due to noise interference from external light sources and increased data complexity

Engineering Contradiction:
Improvenoninvasive measurementVSAvoidcalculation accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent employs periodic pulsed laser irradiation at a constant cycle, where the laser is turned on and off in regular intervals. The detection signal is processed by extracting only the time segments corresponding to the laser on-periods, effectively separating the measurement signal from continuous background noise. This periodic action allows noninvasive measurement while significantly improving calculation accuracy by eliminating noise interference from external light sources.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The patent segments the continuous detection signal into discrete time segments corresponding to each laser pulse cycle. By dividing the measurement process into distinct time segments (laser on-period and off-period), the system can isolate and analyze only the relevant signal portions while discarding noise from other time periods. This segmentation approach resolves the contradiction by maintaining noninvasive operation while enhancing measurement precision through selective signal processing.

Inventive Principle:
Principle #1Segmentation

2Reliability

If continuous monitoring of patient condition is performed with multiple variables, then comprehensive physiological information is obtained, but the device complexity and data processing burden increase

Engineering Contradiction:
Improvephysiological parameter characterizationVSAvoiddata processing complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent uses periodic pulsed laser irradiation with a constant cycle to monitor blood analytes, enabling continuous physiological monitoring through repeated measurements. Each pulse cycle provides a complete measurement sequence (irradiation and detection), allowing comprehensive physiological information to be accumulated over time while maintaining systematic and manageable data processing through the regular periodic structure.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The patent performs preliminary processing of the detection signal by immediately segmenting it into time segments corresponding to laser pulse cycles. This preliminary action of organizing raw data into structured time segments during the measurement process itself simplifies subsequent analysis and reduces the overall data processing burden, while still enabling comprehensive physiological monitoring through continuous repeated measurements.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables noninvasive, low-noise measurement of lactic acid in blood by refining data through time segment analysis, enhancing measurement precision and reducing the need for invasive sample collection.

Implementation Method 1

a laser oscillator that oscillates a pulsed laser beam oscillated at a suitable wavelength associated with a measuring target substance

Methodology Applied
Scientific EffectAbsorption Spectroscopy: Absorption Spectroscopy

Implementation Method 2

a laser oscillator that oscillates a pulsed laser beam oscillated at a suitable wavelength associated with a measuring target substance

Methodology Applied
Scientific EffectLaser: Laser

Implementation Method 3

a photodetector that receives reflected light from the measurement target portion and detects intensity of the reflected light

Methodology Applied
Scientific EffectPhotoelectric Effect: Photoelectric Effect

Data Source

PatentEP4353150B1Biological information detection device and biological information detection method
Publication Date: 2025.12.24 FUJITA MEDICAL INSTR CO LTD
  • EP4353150B1 patent drawingFigure 1~2
  • EP4353150B1 patent drawingFigure 3
  • EP4353150B1 patent drawingFigure 4

AI summary

The present invention is a biological information detection device including: a laser oscillator that oscillates a pulsed laser beam oscillated at a suitable wavelength associated with a measuring target substance; an irradiation mechanism that emits the pulsed laser beam to a liquid biological object inside which the measuring target substance exists; a light receiving sensor that receives a detected laser beam output from the liquid biological object; and a control unit that controls operations of respective components. The control unit outputs an oscillation instruction to the laser oscillator so as to oscillate the pulsed laser beam at a constant cycle, cuts out a detected signal received from the light receiving sensor as time segment data for a time period corresponding to the constant cycle, and calculates a quantity of the measuring target substance in the liquid biological object based on the time segment data.