Pulsed Laser Device for Regenerative Therapy

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Solution Overview

Problem

Low Level Laser Therapy (LLLT) results in inconsistent and slow therapeutic effects due to a lack of understanding of its mechanisms, leading to variable outcomes depending on dosage, exposure rhythm, and tissue distance from the laser source, and is limited to inducing only photochemical and photothermal effects.

Innovation Solution

A device employing a pulsed laser source with a peak intensity fluence (PIF) of 0.1 to 1.0 J/cm³, capable of inducing photomechanical, photothermal, and photochemical effects through controlled peak intensity, pulse duration, and duty cycle, allowing for deeper tissue penetration and regenerative therapy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If Low Level Laser Therapy (LLLT) is used with power between few mW and 1,000 mW, then the therapy can be applied safely to tissue, but the therapeutic results are obtained slowly and are inconsistent

Engineering Contradiction:
Improveconsistency of therapeutic resultsVSAvoidspeed of therapeutic effect
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent changes the key parameter of laser power from low levels (few mW to 1,000 mW) to high intensity levels (above 1,000 mW), specifically using pulsed laser beams with peak intensities of 1,000-50,000 mW. This parameter change enables both fast and consistent therapeutic results while maintaining safety through controlled pulse duration and duty cycle

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs pulsed laser emission rather than continuous low-level emission. The periodic pulsed action with specific duty cycles (1-100%) allows high peak power delivery while providing rest periods, achieving both rapid therapeutic effects and tissue safety, thereby improving consistency and speed of results

Inventive Principle:
Principle #19Periodic action

2Productivity

If high intensity pulsed laser beam is used with peak intensity fluence (PIF) of 0.1 to 1.0 J/cm³, then photomechanical, photothermal, and photochemical effects are induced for faster tissue regeneration, but the risk of tissue damage increases

Engineering Contradiction:
Improvespeed of tissue regenerationVSAvoidrisk of tissue damage
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The pulsed laser delivery system delivers high intensity energy in periodic bursts rather than continuous exposure. By controlling pulse duration (microseconds to seconds) and duty cycle (1-100%), the system induces rapid photomechanical, photothermal, and photochemical effects during pulse peaks while allowing thermal dissipation during off-periods, thus achieving fast regeneration without tissue damage

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The patent maintains continuous therapeutic action through optimized pulse sequences and duty cycles. The overlapping of pulse effects and continuous energy delivery at controlled intervals ensures sustained regenerative stimulation while preventing thermal accumulation that could cause tissue damage, bridging the gap between high intensity and safety

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device achieves faster and more consistently reproducible results by inducing photomechanical, photothermal, and photochemical effects, promoting tissue regeneration and cell proliferation while maintaining tissue temperature within safe limits, unlike traditional LLLT which only achieves photochemical and photothermal effects.

Implementation Method 1

A pulsed laser beam having a peak intensity fluence (PIF) of 0.1 to 1.0 J/cm³ is capable of inducing photomechanical, photothermal and photochemical effects

Methodology Applied
Scientific EffectPhotomechanical effect:

Implementation Method 2

A pulsed laser beam having a peak intensity fluence (PIF) of 0.1 to 1.0 J/cm³ is capable of inducing photomechanical, photothermal and photochemical effects

Methodology Applied
Scientific EffectPhotothermal effect:

Implementation Method 3

A pulsed laser beam having a peak intensity fluence (PIF) of 0.1 to 1.0 J/cm³ is capable of inducing photomechanical, photothermal and photochemical effects

Methodology Applied
Scientific EffectPhotochemical effect:

Implementation Method 4

an optical fiber configured to convey the pulsed laser beam from the pulsed laser source

Methodology Applied
Scientific EffectOptical fiber transmission: Optical Fibre

Implementation Method 5

a focusing tip configured to focus the pulsed laser beam in order to form a spot having a radius r, wherein a diameter of the spot formed by the focusing tip is from 1 millimeter to 20 millimeters

Methodology Applied
Scientific EffectOptical focusing: Focusing

Data Source

PatentEP2358436B1Device for regenerative therapy by high intensity laser therapy
Publication Date: 2015.08.05 EL EN SPA
  • EP2358436B1 patent drawingFigure 1
  • EP2358436B1 patent drawingFigure 2
  • EP2358436B1 patent drawingFigure 3A~3C

AI summary

A method of high intensity laser treatment for stimulating regeneration of living biological tissue in a patient by applying a pulsed laser beam to a skin of the patient in need of the treatment.