PVC Activation Map Merging for Cardiac Lead Positioning

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Solution Overview

Problem

Current methods for determining the optimal location for electrical leads in cardiac resynchronization therapy (CRT) and catheter ablation are inefficient, relying on guesswork and lacking directional guidance for achieving desired electrical activation patterns.

Innovation Solution

The method involves generating a premature ventricular contraction (PVC) activation map based on a 3D heart model and PVC electrocardiogram (ECG) data, merging it with a 3D internal surface model, and pacing the heart at the area of earliest activation identified in the PVC activation surface model using an electrophysiology (EP) catheter.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If current methods are used to determine lead positioning for CRT and ablation, then the procedure can be performed with simple equipment, but the positioning accuracy is poor and relies on guesswork

Engineering Contradiction:
Improvelead positioning accuracyVSAvoidmapping system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system performs preliminary 3D mapping of the heart's electrical activation patterns before lead placement. By pre-identifying the area of earliest activation through PVC activation mapping, the system provides advance guidance for optimal lead positioning, eliminating guesswork and improving positioning accuracy before the actual CRT or ablation procedure begins.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system creates a 3D computational model (virtual copy) of the heart's electrical activity based on ECG data and anatomical information. This virtual model allows physicians to visualize and analyze activation patterns without physical intervention, then transfer this knowledge to guide actual lead placement, improving precision without proportionally increasing physical device complexity.

Inventive Principle:
Principle #26Copying

2Ease of operation

If 3D activation mapping and model merging are implemented, then directional guidance for lead positioning is achieved, but the procedure time and computational requirements increase

Engineering Contradiction:
Improvedirectional guidance for lead positioningVSAvoidprocedure time
Core Design Contradiction:
Ease of operationVSLoss of time

Solution Approach 1:

The system replaces manual trial-and-error mechanical positioning with computational 3D mapping and visualization. By substituting physical guesswork with computer-based activation pattern analysis, the system provides automatic directional guidance that actually reduces overall procedure time despite the added computational step, as physicians no longer need to perform multiple trial placements.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The 3D activation map serves as an intermediary between the patient's electrical activity and the physician's lead placement decisions. This computational intermediary translates complex electrical signals into intuitive visual guidance, bridging the gap between measurement data and clinical action, thereby improving ease of operation without requiring the physician to directly interpret raw ECG data.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If PVC activation mapping is used to identify optimal stimulation locations, then ablation effectiveness is improved, but the measurement and data processing complexity increases

Engineering Contradiction:
Improveablation effectivenessVSAvoidPVC activation pattern analysis
Core Design Contradiction:
ReliabilityVSDifficulty of detecting and measuring

Solution Approach 1:

The system transitions from 2D ECG lead placement to 3D spatial mapping of activation patterns. By adding the spatial dimension to the analysis, the system can identify the precise 3D location of earliest activation within the heart's volume, providing more reliable ablation targets than traditional 2D surface ECG methods alone.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

The 3D mapping system serves multiple functions: it identifies PVC origins for ablation, determines optimal CRT lead positions, and provides directional guidance for both procedures. This multi-functional approach consolidates several measurement tasks into a single comprehensive system, reducing the overall difficulty of detection and measurement despite the increased complexity of individual analyses.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS11246662B2Methods of cardiac mapping and model merging
Publication Date: 2022.02.15 KARDIONAV INC
  • US11246662B2 patent drawing
  • US11246662B2 patent drawing
  • US11246662B2 patent drawing

AI summary

Various embodiments provide a cardiac mapping and model merging method including: generating a premature ventricular contraction (PVC) activation map of a heart based on a three-dimensional (3D) heart model and PVC electrocardiogram (ECG) data recording during PVC of the heart; generating a 3D internal surface model of the heart by triangulating point-by-point contact data collected during an electrophysiology (EP) procedure; merging the 3D activation map and the 3D internal surface model to form a PVC activation surface model; and pacing the heart at a first pacing location disposed in an area of earliest activation identified in PVC activation surface model.