Pyrazole Derivatives for Potent Multi-Mode Pest Control

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Solution Overview

Problem

Current pyrazole derivatives for pest control lack effective and potent insecticidal, acaricidal, molluscicidal, and nematicidal properties, necessitating the development of more potent compounds.

Innovation Solution

The development of specific pyrazole derivatives with defined structural formulas, including various substituents and functional groups, which exhibit enhanced pesticidal activity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If current pyrazole derivatives are used for pest control, then basic pesticidal function is provided, but insecticidal, acaricidal, molluscicidal and nematicidal properties are insufficient

Engineering Contradiction:
Improvepesticidal efficacyVSAvoidpest control effectiveness
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent applies parameter changes by systematically modifying the chemical structure of pyrazole derivatives through various substitutions at positions R1, Q, L, T, and D1-D5. These structural parameter changes result in compounds with significantly enhanced insecticidal, acaricidal, molluscicidal and nematicidal properties compared to parent pyrazole structures

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates composite molecular structures by combining pyrazole core with diverse functional groups including heteroaryl rings, alkyl chains, and substituent patterns. This composite approach yields compounds with superior pesticidal activity across multiple pest types

Inventive Principle:
Principle #40Composite materials

2Reliability

If higher application rates are used to achieve effective pest control, then sufficient pesticidal activity is achieved, but the cost and environmental impact increase

Engineering Contradiction:
Improvepest control efficacyVSAvoidapplication rate
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

By optimizing molecular parameters through specific substitutions on the pyrazole core, the patent achieves high pesticidal potency that allows effective pest control at reduced application rates, thereby decreasing the quantity of substance required

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS11472797B2Pesticidally active pyrazole derivatives
Publication Date: 2022.10.18 SYNGENTA CROP PROTECITON AG
  • US11472797B2 patent drawing
  • US11472797B2 patent drawing
  • US11472797B2 patent drawing

AI summary

Compounds of formula (I) as defined herein, to processes for preparing them, to pesticidal, in particular insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to methods of using them to combat and control pests such as insect, acarine, mollusc and nematode pests.