Pyridine Carboxylate Compositions with Cloquintocet for Crop Selectivity

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Solution Overview

Problem

Existing herbicides often cause phytotoxicity to desirable crops, necessitating the development of safened compositions that minimize harm to crops while effectively controlling undesirable vegetation.

Innovation Solution

The use of safened compositions comprising pyridine carboxylate herbicides, such as cyanomethyl 4-amino-3-chloro-5-fluoro-6-(7-fluoro-1H-indol-6-yl)pyridine-2-carboxylate and propargyl 4-amino-3-chloro-5-fluoro-6-(7-fluoro-1H-indol-6-yl)pyridine-2-carboxylate, combined with the safener cloquintocet, in specific weight ratios to control undesirable vegetation with minimal impact on crops.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If pyridine carboxylate herbicides are used to control undesirable vegetation, then herbicidal effectiveness is improved, but phytotoxicity to desirable crops increases

Engineering Contradiction:

Improveherbicidal effectivenessVSAvoidphytotoxicity to crops

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

A safener compound is introduced as an intermediary substance that selectively protects desirable crops from herbicide damage. The safener acts as a mediator between the herbicide and the crop, enabling the herbicide to control weeds while the safener prevents harm to the crop through selective biochemical interactions.

Inventive Principle:

Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent combines the pyridine carboxylate herbicide with a safener compound to create a composite herbicidal composition. This composite formulation integrates two substances with different functions: the herbicide for weed control and the safener for crop protection, achieving both effectiveness and selectivity simultaneously.

Inventive Principle:

Principle #40Composite materials

2Reliability

If herbicidal compositions are applied to control vegetation, then control effectiveness is improved, but selectivity between desirable and undesirable vegetation deteriorates

Engineering Contradiction:

Improvecontrol effectivenessVSAvoidselectivity

Core Design Contradiction:

ReliabilityVSAdaptability or versatility

Solution Approach 1:

The safener serves as a selective intermediary that differentiates between desirable and undesirable vegetation responses. It selectively interacts with biochemical pathways in desirable crops to provide protection, while having minimal effect on weed control, thereby enhancing selectivity without compromising overall control effectiveness.

Inventive Principle:

Principle #24Intermediary (Mediator)

Solution Approach 2:

The safener provides localized protection specifically to desirable crops through selective biochemical interactions. This local quality approach ensures that the protection is targeted at crop plants while allowing the herbicide to maintain its effectiveness against weeds, creating spatial and functional differentiation in the system.

Inventive Principle:

Principle #3Local quality

Data Source

PatentEP3876722B1Safened compositions comprising pyridine carboxylate herbicides and cloquintocet

Publication Date: 2025.09.10 CORTEVA AGRISCIENCE LLC

AI summary

Disclosed herein are safened compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt or ester thereof and (b) a quinolinoxy acetate safener or agriculturally acceptable salt or ester thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt or ester thereof and (b) a quinolinoxy acetate safener or agriculturally acceptable salt or ester thereof.