Synergistic Herbicidal Composition of Pyridine Carboxylic Acid and Propyzamide

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Solution Overview

Problem

Current herbicides are inadequate in effectively controlling undesirable vegetation in agriculture, necessitating the development of new compositions and methods that offer improved herbicidal activity and synergistic effects.

Innovation Solution

The use of a compound of formula (4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-pyridine-2-carboxylic acid or its agriculturally acceptable salts or esters in combination with propyzamide, which can be applied alone or with adjuvants and carriers to achieve synergistic herbicidal effects, providing control over a wide range of weeds in various crops and non-crop situations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If current herbicides are used alone, then application simplicity is maintained, but herbicidal effectiveness is insufficient

Engineering Contradiction:
Improveherbicidal effectivenessVSAvoidcomposition complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines compound (I) with propyzamide to create a synergistic herbicidal composition. This merging of two different herbicidal agents with distinct modes of action (HPPD inhibition and ACCase inhibition) produces enhanced weed control effectiveness that exceeds the sum of individual activities, resolving the contradiction between simplicity and effectiveness by creating a unified composition that delivers superior performance.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention employs a composite herbicidal system comprising compound (I) and propyzamide in specific ratios. This composite approach leverages the complementary mechanisms of action between the two compounds, where compound (I) inhibits HPPD and propyzamide inhibits ACCase, creating a multi-target herbicidal strategy that overcomes weed resistance and enhances overall efficacy while maintaining manageable composition complexity.

Inventive Principle:
Principle #40Composite materials

2Adaptability or versatility

If a single herbicide is applied, then application cost is reduced, but weed control spectrum is limited

Engineering Contradiction:
Improveweed control spectrumVSAvoidherbicide dosage
Core Design Contradiction:
Adaptability or versatilityVSQuantity of substance

Solution Approach 1:

The herbicidal composition achieves multi-functionality by combining compound (I) and propyzamide, enabling control over a broad spectrum of weed types including grasses, broadleaf weeds, and sedges. This universal approach allows a single composition to address diverse weed infestations that would otherwise require multiple different herbicides, expanding the control spectrum without proportionally increasing dosage requirements due to synergistic effects.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If herbicide combinations are used, then herbicidal activity is enhanced, but formulation complexity increases

Engineering Contradiction:
Improveherbicidal activityVSAvoidformulation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent optimizes the formulation by establishing specific concentration ranges for compound (I) and propyzamide that maximize synergistic herbicidal activity while maintaining formulation simplicity. By defining precise parameter ranges (0.1-98% w/w for compound (I) and 0.1-98% w/w for propyzamide), the invention achieves enhanced reliability through synergistic interaction without excessive formulation complexity, allowing for practical manufacturing and application.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP2947988B9Herbicidal compositions comprising 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid
Publication Date: 2019.01.23 DOW AGROSCIENCES LLC
  • EP2947988B9 patent drawing
  • EP2947988B9 patent drawing
  • EP2947988B9 patent drawing

AI summary

Herbicidal compositions and methods of controlling undesirable vegetation using a combination of (a) a compound of formula (I): (structurally represented) or an agriculturally acceptable salt or ester thereof and (b) propyzamide provide control of undesirable vegetation, e.g., in winter/spring oilseed rape, winter/spring canola, vegetables, Brassica spp, ornamentals, rice, wheat, triticale, barley, oats, rye, sorghum, com/maize, sunflower, row crops, pastures, grasslands, rangelands, fallowland, sugarcane, turf, tree and vine orchards, and industrial vegetation management and rights-of-way.