Substituted Pyrrolone Derivatives for Selective Weed Control
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current herbicidal pyrrolones lack alternative compounds with improved potency, spectrum of activity, and selectivity compared to existing herbicides.
Innovation Solution
Development of novel substituted pyrrolone derivatives with specific functional groups and structures that enhance herbicidal activity, including compounds of the formula (I) with varied substituents, which can be used in herbicidal compositions and methods for controlling weeds.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If existing herbicidal pyrrolones are used, then herbicidal activity is achieved, but potency and spectrum of activity are insufficient
Solution Approach 1:
The patent applies parameter changes by systematically varying substituents at multiple positions (R1-R6, R8-R10) on the pyrrolone core structure, including different halogens, alkyl groups, alkoxy groups, and heterocyclic rings, to optimize herbicidal activity and broaden spectrum of activity across different weed species
Solution Approach 2:
The patent creates composite molecular structures by combining the pyrrolone core with various heterocyclic rings (isoxazole, triazole, pyrimidine) and diverse substituent groups, resulting in hybrid compounds that exhibit enhanced and broadened herbicidal activity compared to simpler analogs
2Reliability
If existing herbicidal pyrrolones are used, then herbicidal function is provided, but selectivity is insufficient
Solution Approach 1:
The patent applies local quality by introducing specific substituent patterns at particular positions on the pyrrolone ring system, such as halogen atoms at R1-R2 positions and specific heterocyclic groups at R3-R6 positions, to enhance selectivity for weed species while preserving herbicidal function and reducing impact on desirable crops
3Reliability
If novel substituted pyrrolone derivatives are developed, then potency and spectrum of activity are improved, but compound complexity increases
Solution Approach 1:
The patent applies segmentation by dividing the herbicidal agent into a modular structure consisting of a pyrrolone core with distinct substituent regions (R1-R6, R8-R10), allowing systematic optimization of individual positions to enhance potency while maintaining a manageable structural framework for synthesis and characterization
Data Source
AI summary
The invention relates to pyrrolone compounds of the formula (I) wherein X, Rb, Rc, R1, R2 and R3 are as defined in the specification. Furthermore, the present invention relates to processes and intermediates for making compounds of formula (I), to herbicidal compositions comprising these compounds and to methods of using these compounds to control plant growth.