Quadrupole Collision Cell Ion Acceleration for Low-Crosstalk Transmission

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Solution Overview

Problem

Prior collision reaction cell ion acceleration apparatuses with extremely low crosstalk suffer from low transmission efficiency and inability to adjust the motion trajectory of charged ions, leading to reduced working efficiency.

Innovation Solution

The apparatus includes a vacuum cavity, first and second tube bundle channels, drift tube support rods, radio-frequency quadrupole electrodes, high-frequency electric quadrupole lenses, and collision chambers, forming a fast transmission and acceleration mechanism that utilizes electric fields and collision gas to stabilize and accelerate ions, with T-shaped plates and insulation bases for stability and safety.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If a prior collision reaction cell ion acceleration apparatus with extremely low crosstalk is used, then the apparatus structure is simple, but the transmission efficiency of charged ions is low

Engineering Contradiction:
Improveapparatus structureVSAvoidtransmission efficiency
Core Design Contradiction:
Device complexityVSProductivity

Solution Approach 1:

The apparatus is divided into multiple functional modules including a radio frequency quadrupole acceleration module with four electrode sets, a collision reaction cell module with collision chamber and gas injection system, and a detection module. Each module performs a specific function in the ion acceleration and detection process, improving overall transmission efficiency through specialized functional segmentation.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The apparatus employs dynamic control of electrode potentials and radio frequency fields to optimize ion transmission. The radio frequency quadrupole electrodes dynamically adjust electric fields to guide and accelerate ions, while the collision chamber dynamically introduces collision gas to modify ion trajectories and improve transmission through the apparatus.

Inventive Principle:
Principle #15Dynamics

2Device complexity

If a prior collision reaction cell ion acceleration apparatus with extremely low crosstalk is used, then the apparatus structure is simple, but the ability to adjust motion trajectory of charged ions is poor

Engineering Contradiction:
Improveapparatus structureVSAvoidtrajectory adjustment capability
Core Design Contradiction:
Device complexityVSAdaptability or versatility

Solution Approach 1:

The radio frequency quadrupole electrodes provide dynamic trajectory control through time-varying electric fields that can steer and focus ion beams. The collision chamber dynamically introduces collision gas at controlled rates to modify ion trajectories through controlled collisions, enabling adaptable trajectory adjustment without increasing overall apparatus complexity.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The apparatus adjusts trajectory by changing operational parameters including radio frequency field strength and frequency, electrode potentials, and collision gas flow rate. These parameter changes enable flexible control of ion motion trajectories while maintaining a relatively simple apparatus structure.

Inventive Principle:
Principle #35Parameter changes

3Device complexity

If the apparatus cannot change motion trajectory of charged ions well, then the apparatus structure is simple, but the working efficiency is reduced

Engineering Contradiction:
Improveapparatus structureVSAvoidworking efficiency
Core Design Contradiction:
Device complexityVSProductivity

Solution Approach 1:

The apparatus segments the ion manipulation process into distinct functional zones: the radio frequency quadrupole section for initial acceleration and trajectory control, the collision reaction cell section for trajectory modification through gas collisions, and the detection section. This segmentation enables efficient ion transmission by optimizing each section's function.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The collision gas introduced in the collision chamber serves as an intermediary medium to modify ion trajectories. By controlling the amount and type of collision gas, the apparatus can efficiently adjust ion paths and improve working efficiency without requiring complex mechanical trajectory adjustment mechanisms.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This configuration enhances the transmission efficiency and stability of charged ions by accelerating them through electric fields and allowing them to form new trajectories, improving the overall working efficiency of the apparatus.

Implementation Method 1

due to a field of an electrode electric field formed in the acceleration gap on an outer side of the radio-frequency quadrupole electrode, the charged ions can be accelerated during transmission

Methodology Applied
Scientific EffectElectric field: Electric Field

Implementation Method 2

High-frequency electric quadrupole lenses are fixedly connected on both sides of the collision chamber

Methodology Applied
Scientific EffectElectric field: Electric Field

Implementation Method 3

after fully reacting with a collision gas, the entered charged ions moving irregularly may form a new motion trajectory in the collision chamber

Methodology Applied
Scientific EffectCollision: Impact Force

Data Source

PatentUS11929244B2Collision reaction cell ion acceleration apparatus with extremely low crosstalk
Publication Date: 2024.03.12 NANJING PINSHENG MEDICAL TECH CO LTD
  • US11929244B2 patent drawing
  • US11929244B2 patent drawing

AI summary

A collision reaction pool ion acceleration apparatus which has extremely low crosstalk. The apparatus comprises an apparatus body, a vacuum chamber, a first tube bundle channel and a second tube bundle channel. The vacuum chamber is fixedly connected to the interior of the apparatus body; the other end of the interior of the apparatus body is fixedly connected to a first insulation seat. A collision chamber is embeddedly connected to the inside the first insulation seat, and a high-frequency electrode quadrupole lens is fixedly connected to two sides of the collision chamber. When charged ions enter the collision chamber, the high-frequency electrode quadrupole lens focuses on the charged ions, so that the incoming charged ions form a new motion trajectory in the collision chamber, and the charged ions are easily separated from the collision chamber, thereby increasing the working efficiency.