Quartz Microfluidic Chip Fabrication Using Femtosecond Plasma Gratings

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Solution Overview

Problem

Current femtosecond laser processing methods for microfluidic chip manufacturing face challenges such as slow processing speed, high time consumption, short focal depth, and difficulties in manufacturing millimeter-sized microchannels, along with irregular optical filament distribution and sputtered particles affecting efficiency.

Innovation Solution

The method involves converging two or more femtosecond pulse laser beams at a certain included angle in quartz glass to form a plasma grating, with synchronized pulses creating equidistant optical filaments that are controlled to ablate microchannels, followed by immersion in hydrofluoric acid to form the microfluidic chip structure.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If single beam femtosecond laser is used for point-by-point ablation, then processing precision is maintained, but processing speed becomes slow and time consumption increases

Engineering Contradiction:
Improvemicrochannel processing precisionVSAvoidprocessing speed
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The single laser beam is segmented into multiple beams through a beam splitter, creating multiple optical filaments that process different regions simultaneously. This segmentation allows parallel processing of microchannels, significantly improving processing speed while maintaining precision through controlled interference patterns of the divided beams

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Multiple laser beams are combined through interference to create a plasma grating pattern with equidistant optical filaments. The merging of multiple beams constructively interferes to form regular, evenly spaced filaments that enable both high-speed parallel processing and precise microchannel formation through the interference pattern geometry

Inventive Principle:
Principle #5Merging (Combining)

2Productivity

If laser energy is increased to improve ablation efficiency, then processing speed increases, but optical filaments become irregularly distributed and processing precision decreases

Engineering Contradiction:
Improveablation efficiencyVSAvoidoptical filament distribution regularity
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The interference pattern of multiple beams is established before ablation occurs, creating a pre-defined plasma grating structure with equidistant optical filaments. This preliminary structuring constrains the high-energy laser ablation to follow precise, regular paths, preventing the irregular filament distribution that would otherwise occur at high energies

Inventive Principle:
Principle #9Preliminary anti-action

Solution Approach 2:

The system changes the parameter of laser beam configuration from single to multiple beams with specific angular relationships. This parameter change creates an interference pattern that fundamentally alters the energy distribution in the material, enabling regular optical filament formation even at high laser energies that would otherwise produce irregular patterns

Inventive Principle:
Principle #35Parameter changes

3Manufacturing precision

If processing time is extended to improve microchannel quality, then manufacturing precision improves, but productivity decreases

Engineering Contradiction:
Improvemicrochannel wall qualityVSAvoidproduction time
Core Design Contradiction:
Manufacturing precisionVSLoss of time

Solution Approach 1:

Multiple laser beams operate simultaneously and continuously to ablate microchannels along their entire length in a single pass. The continuous interference pattern of the plasma grating enables uninterrupted ablation along the microchannel path, eliminating the need for slow point-by-point processing while maintaining high wall quality through consistent energy delivery

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach significantly increases manufacturing speed, improves microchannel wall roughness, and enables efficient processing of three-dimensional structures with high precision and reduced production time, while maintaining regular filament distribution and minimizing particle sputtering.

Implementation Method 1

two or more beams of femtosecond pulse laser converge in quartz glass at a certain included angle, and interference occurs when pulses are synchronized in time domain; a plurality of optical filaments are formed and arranged equidistantly in space

Methodology Applied
Scientific EffectInterference: Interference

Implementation Method 2

When the self-focusing effect and a plasma self-defocusing effect generated by ionization are balanced, the diameter of a light spot remains almost unchanged in the propagation, and a long white optical filament can be seen in the quartz glass

Methodology Applied
Scientific EffectSelf-focusing effect:

Implementation Method 3

a plasma is controlled to scan and ablate a shape of a microchannel in the quartz glass by adjusting a focal length of a focusing lens and laser energy

Methodology Applied
Scientific EffectLaser ablation: Laser Ablation

Implementation Method 4

The femtosecond pulse laser has characteristics such as threshold damage and multiphoton processes in transparent media, and therefore, the femtosecond pulse laser technology has received extensive attention and research in the field of preparation and processing of high-precision and submicron-scale microstructures

Methodology Applied
Scientific EffectAblation: Ablation

Implementation Method 5

an ablated part of the quartz glass is immersed in hydrofluoric acid to form a microchannel structure

Methodology Applied
Scientific EffectChemical etching:

Data Source

PatentUS11370657B2Method and apparatus for manufacturing microfluidic chip with femtosecond plasma grating
Publication Date: 2022.06.28 SHANGHAI LANGYAN OPTOELECTRONICS TECH CO LTD
  • US11370657B2 patent drawing
  • US11370657B2 patent drawing
  • US11370657B2 patent drawing

AI summary

The present disclosure discloses a method and apparatus for manufacturing a microfluidic chip with a femtosecond plasma grating. The method is characterized in that two or more beams of femtosecond pulse laser act on quartz glass together at a certain included angle and converge in the quartz glass, and when pulses achieve synchronization in time domain, the two optical pulses interfere; Benefited by constraint of an interference field, only one optical filament is formed in one interference period; and numbers of optical filaments are arranged equidistantly in space to form the plasma grating. The apparatus for manufacturing the microfluidic chip includes a plasma grating optical path, a microchannel processing platform, and a hydrofluoric acid ultrasonic cell.