Quercetin Composition Synergy for Bioavailability
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Solution Overview
Problem
Current antioxidant compositions do not effectively enhance physical and mental performance or treat conditions such as mental fatigue, viral infections, and tumors, as they lack synergistic benefits and optimal bioavailability of quercetin when used alone or in combination with other vitamins.
Innovation Solution
A composition containing quercetin, vitamin B3, and vitamin C in specific weight ratios, which can be administered in various forms, including dietary supplements and pharmaceutical formulations, to enhance physical and mental performance and treat various disorders by maintaining higher quercetin plasma levels and extending its half-life.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If quercetin is used alone or in combination with other vitamins, then antioxidant activity is provided, but physical and mental performance enhancement and treatment of conditions such as mental fatigue, viral infections, and tumors are not effectively achieved
Solution Approach 1:
The patent combines quercetin with specific vitamins (B3, B6, B12, C, E) and other antioxidants in defined weight ratios to create a synergistic composition. This merging of multiple active ingredients resolves the contradiction by providing both reliable performance enhancement and versatility in treating various conditions including mental fatigue, viral infections, tumors, and inflammatory diseases.
Solution Approach 2:
The invention creates a composite antioxidant composition with specific weight ratios of quercetin (10-500 mg), vitamin B3 (1-50 mg), vitamin B6 (1-50 mg), vitamin B12 (1-50 mcg), vitamin C (10-500 mg), and vitamin E (1-50 mg). This composite formulation achieves both enhanced reliability for performance improvement and adaptability for treating multiple health conditions simultaneously.
2Reliability
If natural antioxidants are used to inhibit free-radical induced diseases, then antioxidant protection is provided, but synergistic benefits with biologically relevant oxygen species are not fully realized
Solution Approach 1:
The patent merges quercetin with multiple vitamins and antioxidants that work synergistically against biologically relevant oxygen species including hydroxyl radicals, superoxides, oxysulfurs, sulfur dioxide, and nitrogen dioxide. This combination resolves the contradiction by enhancing both antioxidant protection and synergistic action against various reactive oxygen species.
3Reliability
If existing antioxidant compositions are formulated, then basic antioxidant activity is achieved, but optimal bioavailability of quercetin is not maintained
Solution Approach 1:
The patent optimizes the weight ratios of quercetin to co-ingredients (vitamin B3: 0.02-0.5, vitamin B6: 0.02-0.5, vitamin B12: 0.002-0.05, vitamin C: 0.1-5.0, vitamin E: 0.02-0.5) to enhance quercetin bioavailability. This parameter optimization resolves the contradiction by maintaining reliable antioxidant activity while maximizing the quantity of bioavailable quercetin in the composition.
Data Source
AI summary
This invention relates to a composition containing quercetin, vitamin B3, and vitamin C. Also disclosed is a method of using the composition for enhancing physical or mental performance or treating various diseases or disorders.