Radially Expandable Tissue Retraction Device for Lung Volume Reduction

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Solution Overview

Problem

Current lung volume reduction methods are invasive, destructive to the airway, and associated with complications such as bleeding and tissue trauma, lacking reversibility and retrievability.

Innovation Solution

A radially expandable tissue retraction device with atraumatic fixation elements connected by a tether, allowing for secure lung volume reduction without causing significant tissue damage, featuring self-expanding properties and a design that minimizes trauma and bleeding.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional thoracic surgery or invasive ILVR methods are used to achieve lung volume reduction, then effective volume reduction is achieved, but tissue trauma, bleeding, and airway damage occur

Engineering Contradiction:
Improvelung volume reduction effectivenessVSAvoidtissue trauma and bleeding
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The fixation elements use a flexible tubular structure with radial expandability, allowing the device to conform to tissue surfaces without piercing or damaging them. The tubular body can expand to engage tissue externally while maintaining structural integrity, achieving secure fixation without the need for invasive piercing anchors that cause tissue trauma and bleeding.

Inventive Principle:
Principle #30Flexible shells and thin films

2Strength

If traditional piercing anchors are used for fixation, then secure anchoring is achieved, but airway tearing and puncturing occur

Engineering Contradiction:
Improvefixation strengthVSAvoidairway damage
Core Design Contradiction:
StrengthVSObject-affected harmful factors

Solution Approach 1:

Instead of using piercing anchors that penetrate tissue from the inside out, the invention inverts the approach by using external fixation elements that engage tissue from the outside. The radially expandable tubular structure compresses tissue externally to achieve anchoring, reversing the traditional invasive piercing method and eliminating airway puncturing and tearing.

Inventive Principle:
Principle #13The other way round (Inversion)

3Reliability

If permanent ILVR devices are implanted to achieve lung volume reduction, then volume reduction is achieved, but reversibility and retrievability are lost

Engineering Contradiction:
Improvelung volume reduction effectivenessVSAvoidreversibility and retrievability
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The fixation elements incorporate a shape memory alloy or superelastic material that allows the device to transition between compressed and expanded states. This dynamic property enables the device to be deployed in a compressed state, expand to fixed state for lung volume reduction, and potentially be compressed again for retrieval, providing reversibility and adaptability not found in permanent rigid devices.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device enables effective and reversible lung volume reduction with reduced invasiveness, minimizing tissue trauma and bleeding, and allowing for potential retrieval, thereby improving patient safety and quality of life.

Implementation Method 1

Each fixation element is a radially expandable device, which includes a tubular configuration when compressed, but in expanded state the first and second ends of the tube move toward each other and the central region of the tube expands radially to form struts

Methodology Applied
Scientific EffectElastic deformation: Elasticity

Data Source

PatentEP3169247B1Mechanical retraction via tethering for lung volume reduction
Publication Date: 2020.05.13 ETHICON INC
  • EP3169247B1 patent drawingFigure 1~2
  • EP3169247B1 patent drawingFigure 3~5
  • EP3169247B1 patent drawingFigure 6~7

AI summary

A device and method for reducing the volume of a tissue region, the device including a first fixation element, a second fixation element, and a tethering device, where the first and second fixation elements are slidably secured onto said tether, and the first and second fixation elements are radially self-expanding fixation elements.