Radiation Therapy Target Set Determination Using Constraint Masks

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Solution Overview

Problem

Current radiation therapy methods face challenges in effectively avoiding irradiation of risk regions during treatment, especially when multiple spatially disjunct targets or targets surrounding risk regions, such as the prostate or brain structures, need to be treated.

Innovation Solution

A medical data processing method determines a target set for radiation therapy by using constraint masks to differentiate between irradiation and non-irradiation regions based on spatial relationships and predetermined beam arrangements, ensuring that risk regions are avoided during treatment planning.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If multiple spatially disjunct targets are irradiated with individual treatment beams, then each target can be sufficiently irradiated, but risk regions may still be irradiated during relative movement of the patient's body and the treatment beam source

Engineering Contradiction:
Improveirradiation precisionVSAvoidradiation exposure to risk regions
Core Design Contradiction:
Manufacturing precisionVSObject-affected harmful factors

Solution Approach 1:

The patent divides the treatment process into discrete time intervals and separates targets into different sets (first set and second set). Each target set is irradiated during specific time intervals, allowing the treatment beam to be directed at different targets at different times, thereby avoiding simultaneous irradiation of multiple targets and reducing exposure to risk regions.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent employs dynamic adjustment of the treatment beam parameters and patient positioning during treatment. By varying the beam geometry, irradiation time intervals, and relative positions of the patient and treatment beam source, the system adapts to avoid irradiating risk regions while ensuring adequate treatment of all targets.

Inventive Principle:
Principle #15Dynamics

2Manufacturing precision

If the time interval during which each target is irradiated is varied, then each target can be sufficiently irradiated while avoiding damage to risk regions, but treatment time increases

Engineering Contradiction:
Improveirradiation precisionVSAvoidtreatment time
Core Design Contradiction:
Manufacturing precisionVSLoss of time

Solution Approach 1:

The patent implements periodic irradiation cycles where different target sets are treated in alternating time intervals. The first target set is irradiated during first time intervals, followed by second time intervals for the second target set, creating a periodic treatment pattern that optimizes both precision and efficiency.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The patent maintains continuous treatment action by eliminating idle time between irradiation of different target sets. The transition between treating different target sets is optimized to ensure continuous useful irradiation action, minimizing non-productive time while maintaining precision.

Inventive Principle:
Principle #20Continuity of useful action

3Manufacturing precision

If beam geometry is varied for each target, then each target can be sufficiently irradiated while avoiding damage to risk regions, but device complexity increases

Engineering Contradiction:
Improveirradiation precisionVSAvoidtreatment planning complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent applies different beam geometries and irradiation parameters tailored to each specific target set and its spatial relationship to risk regions. Each target receives customized irradiation conditions optimized for its location, ensuring precise treatment while minimizing exposure to surrounding healthy tissues.

Inventive Principle:
Principle #3Local quality

Data Source

PatentEP3047410B1Method and device for improved radiation therapy treatment of a set of targets
Publication Date: 2019.01.30 BRAINLAB AG
  • EP3047410B1 patent drawingFigure 1
  • EP3047410B1 patent drawingFigure 2
  • EP3047410B1 patent drawingFigure 3

AI summary

A medical data processing method for determining a target set comprising at least one irradiation target in a patient's body for radiation therapy treatment by means of a treatment device constituted to treat the at least one target by means of one or more sub- beams during a treatment time, the one or more sub-beams constituting at least one treatment beam which is to pass through the at least one target in accordance with a treatment plan during the treatment time, the method comprising the following steps and being constituted to be executed by a computer: a) acquiring (S 1.1 ) critical area; b) acquiring (S 1.2) target data; c) acquiring (S 1.3) treatment beam constraint data; d) acquiring treatment beam criteria data (S 1.4); and e) determining (S4), based on the critical area data, the target data, the treatment beam constraint data and the treatment beam criteria data, target set data describing spatial information on at least one irradiation region.