Radiopaque Depth Indicators for Cardiac Tissue Anchor Delivery

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Solution Overview

Problem

Existing technologies face challenges in accurately visualizing and delivering tissue anchors to a precise depth within cardiac tissue due to limitations such as insufficient resolution, fluid overload, and transient contrast injection, making it difficult to perform precise procedures in beating hearts with anatomical irregularities.

Innovation Solution

A tissue anchor delivery device equipped with a tissue depth indicator and optional depth limiter, which includes a tissue depth indicator within a longitudinal lumen to delineate the tissue surface and a depth limiter to prevent excessive penetration, allowing for precise anchor deployment by visual and tactile cues.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of information

If fluoroscopic contrast injection is used to visualize cardiac tissue, then tissue visualization is achieved, but the image quality deteriorates due to transient contrast and heart chamber shape making interpretation difficult

Engineering Contradiction:
Improvetissue visualization qualityVSAvoiddepth of penetration measurement
Core Design Contradiction:
Loss of informationVSMeasurement precision

Solution Approach 1:

A depth indicator wire is introduced as an intermediary element between the delivery catheter and the tissue. The wire extends beyond the catheter tip and provides a visual reference that mediates the measurement of penetration depth, making it easier to interpret fluoroscopic images and determine when the desired depth is reached.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The depth indicator wire incorporates radiopaque segments that appear distinct under fluoroscopy, creating visual contrast changes that help operators track the position and depth of penetration in real-time, improving measurement precision despite the transient nature of contrast injection.

Inventive Principle:
Principle #32Color changes

2Reliability

If electrical sensors are used to signal contact with tissue, then contact detection is achieved, but depth of penetration determination becomes unreliable

Engineering Contradiction:
Improvecontact detectionVSAvoiddepth of penetration
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The depth measurement function is segmented from the electrical contact sensor. The depth indicator wire provides a separate, dedicated visual measurement system that operates independently from the electrical contact detection, allowing each function to perform its specialized role without interference.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The radiopaque depth indicator wire serves as an intermediary visual reference that translates the physical penetration depth into observable fluoroscopic markers, enabling precise depth determination without relying on electrical sensor interpretations.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Duration of action of moving object

If transesophageal echo is used for tissue visualization, then real-time imaging is achieved, but resolution is insufficient for precise procedures

Engineering Contradiction:
Improvereal-time imaging capabilityVSAvoidtissue resolution
Core Design Contradiction:
Duration of action of moving objectVSMeasurement precision

Solution Approach 1:

The fluoroscopic imaging system is enhanced to serve multiple functions: it provides both the real-time imaging capability needed for dynamic procedures and the high resolution required for precise depth measurement, by incorporating the radiopaque depth indicator wire that appears clearly on fluoroscopic images.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentEP4292551B1Devices of visualizing and determining depth of penetration in cardiac tissue
Publication Date: 2025.10.15 ANCORA HEART INC
  • EP4292551B1 patent drawingFigure 1A~1B
  • EP4292551B1 patent drawingFigure 1C~1D
  • EP4292551B1 patent drawingFigure 1E~1F

AI summary

Disclosed herein are devices and methods for assessing the surface of a target cardiac tissue and for delivering a tissue anchor to cardiac tissue at a preselected depth within the myocardium in a beating heart procedure. In one variation, an anchor delivery device comprises an elongate body, a tissue anchor disposed within a first longitudinal lumen of the elongate body, and a tissue depth indicator slidable within a second longitudinal lumen of the elongate body. The tissue depth indicator has a first configuration that indicates the boundary of the surface of the target tissue and a second configuration that indicates when the distal tip of the elongate body has been advanced to a preselected depth into the target tissue. In some variations, a tissue depth indicator may also be configured to resist or limit the penetration of the delivery device into tissue after a preselected depth has been reached.