Computer-Facilitated Radiopharmaceutical Infusion System

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Solution Overview

Problem

The setup, maintenance, and operational procedures for infusion systems that generate and inject radiopharmaceuticals are complex and time-consuming, posing a risk of prolonged exposure to radioactive radiation for technical personnel.

Innovation Solution

A computer-facilitated infusion system with a shielding assembly and ergonomic cabinet structure that includes a touch-screen interface for user input, automatic valve operation, and a light projector for signaling infusion status, allowing for safer and more efficient setup, maintenance, and operation by reducing direct exposure to radiation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of time

If manual setup, maintenance and operational procedures are used for infusion systems, then personnel have direct control and understanding of the system, but radiation exposure time is prolonged and operational efficiency is reduced

Engineering Contradiction:
Improveradiation exposure timeVSAvoidoperational complexity
Core Design Contradiction:
Loss of timeVSEase of operation

Solution Approach 1:

The system performs self-testing and self-diagnosis through automated quality control routines that check generator functionality, tubing integrity, and system parameters without requiring manual intervention. The computer automatically monitors and adjusts infusion parameters, reducing the need for continuous manual oversight and minimizing personnel radiation exposure time.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

Manual mechanical operations are replaced with computer-controlled automated systems. The computer facilitates setup, maintenance and operational procedures by automatically controlling valves, pumps, and monitoring systems, eliminating the need for personnel to manually manipulate radioactive components and significantly reducing radiation exposure time.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Productivity

If automated computer-facilitated procedures are implemented, then radiation exposure is reduced and operational efficiency is improved, but system complexity and initial setup requirements increase

Engineering Contradiction:
Improveoperational efficiencyVSAvoidsystem configuration complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The computer system serves multiple functions including quality control monitoring, infusion parameter control, system diagnostics, and operational automation. This multi-functionality consolidates what would otherwise require multiple separate devices and manual procedures into a single integrated system, improving operational efficiency without proportionally increasing overall system complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system incorporates automated feedback mechanisms where the computer continuously monitors system parameters, quality control metrics, and infusion delivery accuracy. Based on this feedback, the system automatically adjusts operational parameters and alerts personnel to any deviations, enabling efficient automated operation while maintaining system reliability despite increased automation complexity.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS9597053B2Infusion systems including computer-facilitated maintenance and/or operation and methods of use
Publication Date: 2017.03.21 BRACCO DIAGNOSTICS INC
  • US9597053B2 patent drawing
  • US9597053B2 patent drawing
  • US9597053B2 patent drawing

AI summary

Methods for setting up, maintaining and operating a radiopharmaceutical infusion system, that includes a radioisotope generator, are facilitated by a computer of the system. The computer includes pre-programmed instructions and a computer interface, for interaction with a user of the system, for example, in order to track contained volumes of eluant and/or eluate, and/or to track time from completion of an elution performed by the system, and/or to calculate one or more system parameters for quality control, and/or to perform purges of the system.