Radiotherapy Trajectory Optimization via BEV Mesh Connectivity
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Solution Overview
Problem
Current trajectory optimization methods in radiotherapy fail to preserve the geometrical relationship of adjacent apertures, leading to suboptimal radiation delivery and increased MLC contention issues, which degrades the quality of radiation beam trajectories.
Innovation Solution
The TORUS approach maps the connectedness of target regions from the Beam's Eye View (BEV) throughout the delivery coordinate space, using a modified Dijkstra path optimization method to select beam trajectories that maximize angular spread and minimize trajectory interference, thereby improving the synchronization of dynamic delivery in radiotherapy.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If current trajectory optimization methods are used, then computational simplicity is maintained, but geometrical relationship of adjacent apertures is not preserved leading to suboptimal radiation delivery
Solution Approach 1:
The patent segments the delivery coordinate space into discrete vertices and edges, creating a mesh representation that preserves geometrical relationships of adjacent apertures. This segmentation allows the optimization method to maintain spatial connectivity information while managing computational complexity through structured discretization.
Solution Approach 2:
The patent introduces a new dimension by representing the delivery coordinate space as a mesh with vertices connected by edges, adding topological structure to the optimization problem. This dimensional transformation enables preservation of geometrical relationships while maintaining computational tractability through graph-based representation.
2Manufacturing precision
If dynamic delivery capabilities are increased, then dose gradient formation is improved, but MLC contention issues increase degrading trajectory quality
Solution Approach 1:
The patent incorporates feedback by evaluating trajectory quality metrics including MLC contention detection during the optimization process. The mesh-based representation provides feedback on geometrical relationships, allowing the system to adjust trajectories to reduce MLC contention while maintaining dose gradient formation quality.
Solution Approach 2:
The patent employs dynamic optimization by allowing trajectory parameters to be adjusted iteratively based on evaluated performance metrics. The mesh structure enables dynamic evaluation of adjacent aperture relationships, allowing real-time adjustments to reduce MLC contention while preserving dose distribution quality.
3Manufacturing precision
If beam angle optimization is performed, then plan quality is improved, but treatment delivery time increases
Solution Approach 1:
The patent performs preliminary optimization by pre-calculating and storing the mesh representation of the delivery coordinate space with vertices and edges. This preliminary structuring of spatial relationships enables faster subsequent trajectory optimizations, reducing treatment delivery time while maintaining plan quality through pre-established geometrical awareness.
Data Source
AI summary
A radiation therapy treatment method includes providing a patient model, dosimetric constraints, delivery motion constraints, and delivery coordinate space of a radiation delivery device, where the delivery coordinate space is represented as a mesh with vertices connected by edges, where the vertices correspond to directions of a beam eye view (BEV) of the radiation delivery device. BEV region connectivity manifolds are constructed from the patient model, the dosimetric constraints, the delivery coordinate space, and existing beam trajectories, wherein each of the BEV region connectivity manifolds represents connections between contiguous 2D target regions. Beam trajectories are selected based on region connectedness information in the BEV region connectivity manifolds, the dosimetric constraints, the delivery motion constraints, and the existing beam trajectories. Radiation is delivered using the radiation delivery device in accordance with the selected beam trajectories.