Radiotherapy Planning Strategy Selection via Goal Modification Categorization

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Solution Overview

Problem

Existing user-guided iterative planning systems for external beam radiation therapy face challenges in efficiently recalculating treatment plans due to modifications in treatment goals, often resulting in increased computational complexity and uncertainty between warm start and cold start strategies.

Innovation Solution

A system that categorizes modifications to treatment goals and allocates corresponding strategies for treatment plan generation, allowing for automatic determination of optimal strategies between warm start and cold start, utilizing decomposition of calculations into partial optimizations based on added objectives or constraints.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of time

If a warm start strategy is used to recalculate the treatment plan by reusing information from the previous cycle, then computation time is reduced, but the modified treatment goals may not be fulfilled or computational complexity increases

Engineering Contradiction:
Improvecomputation timeVSAvoidfulfillment of modified treatment goals
Core Design Contradiction:
Loss of timeVSReliability

Solution Approach 1:

The system dynamically adapts the recalculation strategy based on the type of modification made to treatment goals. When modifications are minor, a warm start strategy is used to reduce computation time. When modifications are significant, the system switches to a cold start or partial recalculation strategy to ensure treatment goals are fulfilled, thus making the computation process adaptive rather than static

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system changes the recalculation parameters (strategy selection) based on the characteristics of the modifications to treatment goals. By analyzing the type and extent of modifications, the system adjusts the recalculation approach to balance between computation time and goal fulfillment reliability

Inventive Principle:
Principle #35Parameter changes

2Reliability

If a cold start strategy is used to recalculate the treatment plan without reusing information from the previous cycle, then treatment goals are reliably fulfilled, but computational complexity and computation time increase

Engineering Contradiction:
Improvefulfillment of treatment goalsVSAvoidcomputation time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The recalculation process is segmented into different strategies based on modification types. Instead of always performing a complete cold start, the system divides the recalculation into partial optimizations for certain modification types, reducing the overall computational burden while maintaining reliability

Inventive Principle:
Principle #1Segmentation

3Manufacturing precision

If the treatment plan is recalculated from scratch for every modification, then optimal treatment goals are achieved, but the complexity of the calculation increases

Engineering Contradiction:
Improveoptimization accuracyVSAvoidcalculation complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

Instead of always performing a complete recalculation from scratch, the system applies partial optimization by reusing certain information from previous cycles when appropriate. This partial action approach maintains sufficient optimization accuracy while reducing calculation complexity

Inventive Principle:
Principle #16Partial or excessive action

Data Source

PatentEP3400064B1Automatic selection of optimization strategy in iterative treatment planning
Publication Date: 2019.12.18 KONINKLIJKE PHILIPS NV
  • EP3400064B1 patent drawingFigure 1
  • EP3400064B1 patent drawingFigure 2
  • EP3400064B1 patent drawing

AI summary

The invention relates to a system and method for generating a radiotherapy treatment plan on the basis of treatment goals comprising optimization objectives and/or constraints. A planning unit (7) generates a first treatment plan including treatment parameters for fulfilling first treatment goals in a first optimization cycle, and a decision unit (8) receives second treatment goals and compares the first and second treatment goals to 5 determine a modification of the treatment goals, assigns to the modification a category from a plurality of predetermined categories, wherein to each category a strategy from a plurality of predetermined strategies for treatment plan generation is allocated, and instructs the planning unit (7) to generate the second treatment plan in accordance with a strategy allocated to the determined category of modifications in a second optimization cycle.