Raman Spectroscopy Calibration for Ionic Liquid Water Quantification

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Solution Overview

Problem

There is a lack of reliable, in-line, quantitative, and fast analytical methods for the simultaneous determination of ionic liquid components and water molecules in liquid streams, which hinders process monitoring and control in processes like the Ioncell ™< -F process.

Innovation Solution

The development of a method combining Raman spectroscopy with univariate and multivariate calibrations, particularly using partial least squares regression, for the quantitative analysis of protic ionic liquid components and water in ionic liquid/water mixtures, allowing for real-time monitoring and control of processes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional Raman spectroscopy is used for quantitative analysis, then qualitative identification is possible, but quantitative accuracy is insufficient due to variations in scattering intensity

Engineering Contradiction:
Improvequantitative accuracyVSAvoidrepeatability of intensity measurements
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The system employs background correction algorithms that continuously monitor and adjust for intensity variations. The processor compares measured Raman shift positions against reference values and automatically compensates for deviations, creating a feedback loop that maintains quantitative accuracy despite environmental fluctuations or sample heterogeneity.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The invention transforms the measurement approach by changing from direct intensity measurement to frequency shift measurement. By measuring the Raman shift in wavenumbers rather than absolute intensity, the system eliminates the unreliable intensity parameter while preserving quantitative information through the characteristic frequency shifts of molecular vibrations.

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If high resolution Raman spectroscopy is performed, then molecular identification accuracy is improved, but measurement time increases

Engineering Contradiction:
Improvemolecular identification accuracyVSAvoidmeasurement time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs preliminary spectral processing steps including baseline correction, normalization, and enhancement algorithms before final analysis. These pre-processing actions prepare the data for rapid identification, allowing the system to achieve high resolution accuracy without requiring proportionally long measurement times.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The invention creates a digital reference library of Raman spectra for common substances. Instead of requiring time-consuming real-time analysis of every sample, the system compares measured spectra against pre-stored reference copies, enabling rapid identification while maintaining high accuracy through pattern recognition algorithms.

Inventive Principle:
Principle #26Copying

3Measurement precision

If Raman spectroscopy is used for detecting trace substances, then detection capability is improved, but signal-to-noise ratio deteriorates

Engineering Contradiction:
Improvedetection capabilityVSAvoidsignal-to-noise ratio
Core Design Contradiction:
Measurement precisionVSLoss of information

Solution Approach 1:

The system introduces computational intermediaries in the form of advanced signal processing algorithms. These intermediaries include wavelet transform, principal component analysis, and machine learning models that filter noise from the Raman signal, allowing trace substance detection while maintaining high signal-to-noise ratio through intelligent separation of meaningful signals from background noise.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables fast and accurate simultaneous quantification of ionic liquid components and water, ensuring process stability and uniform product quality by providing real-time feedback for process adjustments.

Implementation Method 1

a Raman spectrometer to measure a Raman shift of the incident light

Methodology Applied
Scientific EffectRaman scattering: Scattering

Data Source

PatentEP3990899B1Quantitative raman spectroscopy
Publication Date: 2026.05.20 AALTO UNIV FOUND
  • EP3990899B1 patent drawingFigure 1~2
  • EP3990899B1 patent drawingFigure 3~4
  • EP3990899B1 patent drawingFigure 5~6

AI summary

Disclosed is a method for quantification of water and/or one or more ionic liquid components in an ionic liquid (IL)/water (H2O) mixture. The method comprises obtaining one or more Raman spectra for the IL/H2O mixture, and using a quantitative calibration model with the one or more Raman spectra to quantify water and/or one or more ionic liquid components in the IL/H2O mixture.