Linear Variable Filter Raman Glucose Sensing Without Needles
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Solution Overview
Problem
Existing continuous blood glucose level measuring apparatuses are invasive, causing pain and side effects due to needle insertion, and cannot be used for long-term monitoring.
Innovation Solution
A non-invasive blood glucose level measuring apparatus using Raman spectroscopy, comprising a housing with a light source and light receiver, and a processor to analyze Raman spectra for glucose levels, calibrated to measure glucose, proteins, and fats, with a detachable battery and error detection.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If needle-based invasive measurement is used, then blood glucose level can be measured, but pain and side effects occur
Solution Approach 1:
The patent replaces the mechanical needle-based invasive measurement system with an optical measurement system using Raman spectroscopy. The light source part emits light that interacts with biological tissue, and the light receiving part detects the scattered light to measure glucose levels without physical penetration, thereby eliminating pain and inflammatory reactions while maintaining measurement capability
Solution Approach 2:
The patent introduces light as an intermediary medium to transfer information about glucose levels from the biological tissue to the detector. Instead of direct mechanical contact with a needle, light serves as the mediator that carries spectral information through the tissue, enabling non-invasive measurement and avoiding harmful mechanical effects
2Measurement precision
If needle-based invasive measurement is used, then blood glucose level can be measured, but long-term use is impossible
Solution Approach 1:
The patent replaces the mechanical needle-based system with an optical system that causes no tissue damage. Since there is no physical penetration or tissue disruption, the system can be used continuously over extended periods without the degradation, infection, or tissue damage issues that limit needle-based systems to short-term use
Solution Approach 2:
The patent enables continuous measurement by eliminating the discrete, damaging needle insertion process. The optical system can continuously emit light and detect signals through the tissue without causing cumulative damage, allowing for sustained long-term monitoring that exceeds the 15-day limitation of invasive methods
3Object-affected harmful factors
If Raman spectroscopy is used for non-invasive measurement, then pain and side effects are reduced, but measurement accuracy must be calibrated
Solution Approach 1:
The patent implements preliminary calibration as a preparatory action before actual measurement. The processor performs calibration by controlling the light source and light receiving part to establish baseline relationships between Raman spectral features and glucose concentrations, ensuring subsequent measurements achieve required accuracy while maintaining the non-invasive benefits of the optical system
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables continuous, pain-free glucose monitoring with reduced side effects and improved accuracy by using Raman spectroscopy, allowing long-term use without needle insertion.
Implementation Method 1
a light receiving part disposed in the housing, and that receives the reflected and scattered light from the subject and acquires a Raman spectrum
Data Source
AI summary
Blood glucose level measurement includes a light source configured to irradiate light to a subject; a monochrome part configured to separate wavelength components of the light that is reflected and scattered from the subject; a light receiver configured to receive the light transmitted via the monochrome part and to generate electrical signals based on the received light; and a processor configured to extract information on the blood glucose level of the subject based on a frequency shift of the light due to the Raman effect.