Ramp-Actuated Biological Sample Transfer Device

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Solution Overview

Problem

Current methods for transferring buccal cells to treated storage media are inconsistent and prone to contamination, requiring operator skill and precise pressure and timing, which is not ideal for frequent or less experienced users.

Innovation Solution

A controlled transfer biological collection device with a moveable sample collection member that slides into a transfer position against a dry solid storage medium, using a ramp-like projection to ensure consistent and reproducible transfer, minimizing exposure and risk of contamination.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual manipulation is used to transfer buccal cells to storage medium, then operator flexibility is maintained, but transfer consistency and reproducibility deteriorate

Engineering Contradiction:
Improvetransfer consistencyVSAvoidoperator skill requirement
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The device enables self-service operation where the mechanical structure automatically performs the transfer function when the user simply opens the cap. The collection member is pre-positioned and the storage medium is pre-loaded, eliminating the need for manual manipulation steps that require operator skill.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The cap acts as an intermediary mechanism that, when removed, automatically triggers the transfer of the collection member to the storage medium. This intermediary action standardizes the transfer process, ensuring consistent results regardless of operator experience.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If the collection member is exposed during transfer, then accessibility is improved, but contamination risk increases

Engineering Contradiction:
ImproveaccessibilityVSAvoidcontamination risk
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The storage medium is pre-loaded into the cap before sample collection. The collection member is pre-positioned within the device. When the cap is removed, the transfer occurs automatically, minimizing the time the collection member is exposed and reducing contamination risk.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The collection member is nested within the cap structure during storage and transport. The storage medium is nested within the cap. This nested arrangement protects the collection member from contamination while maintaining easy accessibility through simple cap removal.

Inventive Principle:
Principle #7Nested doll (Nesting)

Data Source

PatentEP3079596B1Controlled transfer biological sample collection devices
Publication Date: 2019.10.02 GLOBAL LIFE SCI SOLUTIONS OPERATIONS UK LTD
  • EP3079596B1 patent drawingFigure 1a~1d
  • EP3079596B1 patent drawingFigure 2a~2d
  • EP3079596B1 patent drawingFigure 3a~3d

AI summary

A controlled transfer biological sample material collection device (100) is disclosed which comprises: a body (112); and a sample collection member (120) for collecting the biological sample material (not shown), the body housing a sample storage medium (30) for generally dry storage of the biological material, the collection member being moveable from an exposed position (shown in Figure 8) where collection of a biological sample is possible, to a transfer position (shown in Figure 9) which effects transfer of at least a portion of the collected sample to said medium. The device is characterised in that the body slideably supports the sample collection member, and in that the body or collection member include a ramp–like projection portion (116 Figure 10) operable to force the collection member into the transfer position against the medium and to effect said transfer as the collection member slides within the body.