Rapamycin DHEA CBD Composition for Mammal Lifespan Extension
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Solution Overview
Problem
Existing anti-aging therapies face challenges in achieving predictable and safe absorption and delivery of anabolic hormones, often resulting in undesired side effects and toxicity due to improper distribution and metabolism.
Innovation Solution
A system and method combining rapamycin with a non-toxic anabolic hormone, such as DHEA, and cannabidiol (CBD), to enhance absorption and localized effect, utilizing a cannabinoid compound to target intestinal mucosa and improve buccal uptake, thereby minimizing systemic toxicity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If anabolic hormones are administered to improve health and longevity, then quality of life is improved, but toxicity and side effects increase
Solution Approach 1:
The patent uses CBD as an intermediary substance that facilitates the delivery and absorption of anabolic hormones through intestinal mucosa, allowing the hormones to reach target tissues more efficiently and reducing the required dosage, thereby improving quality of life while minimizing toxicity
Solution Approach 2:
The patent employs prohormones that are converted to active hormones locally at target tissues rather than circulating systemically. This localized activation ensures that active hormones are produced only where needed, reducing exposure of non-target organs to harmful levels of active hormones while maintaining therapeutic benefits
2Duration of action of stationary object
If anabolic hormones are administered to extend lifespan, then longevity is improved, but absorption and delivery predictability worsen
Solution Approach 1:
CBD acts as a mediator that enhances and standardizes the absorption of anabolic hormones through intestinal mucosa, making the delivery process more predictable and reliable across different individuals and dosing conditions
Solution Approach 2:
The patent utilizes the body's natural enzymatic conversion processes to transform prohormones into active hormones at controlled rates depending on local tissue conditions. This parameter-based conversion (controlled by local enzyme activity rather than fixed dosing) improves the predictability of hormone availability and duration of action
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This combination significantly improves the quality of life and extends lifespan in humans and mammals by facilitating controlled and efficient delivery of health and longevity-enhancing therapies, reducing side effects and toxicity.
Implementation Method 1
Biodelivery and the availability of the rapamycin and prohormone are improved by using a cannabinoid substance, preferably cannabidiol (CBD) or a derivative, to target 'delivery to intestinal mucosa and/or improve buccal uptake'
Implementation Method 2
Absorption of the rapamycin and prohormone in the food is stimulated to occur with a more rapid and more controlled delivery through buccal or mucosal cells into the bloodstream
Implementation Method 3
The prohormone of the composite therapeutic agent is carried by the circulatory system to its site of action where the cells of a tissue or organ processes and/or metabolizes the prohormone to become a locally active hormone
Implementation Method 4
where the cells of a tissue or organ processes and/or metabolizes the prohormone to become a locally active hormone
Data Source
AI summary
The present invention discloses a system and method for increasing the lifespan and quality of life of human beings and other mammals. This discloses methods for preparing and delivering various health and longevity compositions. The compositions of the present invention are selected and designed for the purpose of efficiently delivering health and longevity enhancing therapies through oral supplementation, misting, nasal spray, suppository, etc. An existing compound known to have capacity for life extending potential, rapamycin, is combined with a non-toxic therapeutic anabolic hormone, e.g., DHEA, and cannabidiol (CBD) to enable absorption and effect. These three compounds work together to dramatically improve both the quality of life in aging humans and other mammals as well as extending the life of humans potentially up to 120 healthy years. One preferred embodiment provides a method for continuous low dose supplementation, e.g., incorporated in or with a daily meal. This invention not only resolves the issue of anti-aging of higher life forms, without toxicity, but provides for an improved method for absorption.