Rare Sugar Cariostatic Agent Resolving Stability and Flavor Trade-offs
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Solution Overview
Problem
Current alternative sugars for preventing dental caries, such as Xylitol, have limitations in stability, flavor impact, and effectiveness when used in oral compositions, and there is a need for a non-cariogenic material that can serve as a durable alternative to sucrose and glucose while also providing cariostatic properties.
Innovation Solution
A novel non-cariogenic rare sugar, specifically D-psicose, D-sorbose, D-tagatose, L-fructose, L-psicose, or allitol, which cannot be metabolized by Streptococcus mutans, is blended with catechins to create a cariostatic agent that suppresses acidification and bacterial proliferation, forming a composition that can be used in various oral and food products.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If alternative sugars such as Xylitol are used to prevent dental caries, then caries prevention effect is improved, but stability in oral compositions deteriorates
Solution Approach 1:
The patent changes the chemical parameter of the sugar substitute from conventional options like Xylitol to rare sugars (D-psicose, D-sorbose, D-tagatose, L-fructose, L-psicose, or allitol). These rare sugars possess unique metabolic properties that prevent caries while providing improved stability in oral compositions, thereby resolving the contradiction between caries prevention effectiveness and compositional stability.
2Reliability
If alternative sugars are used to prevent dental caries, then caries prevention effect is improved, but flavor impact deteriorates
Solution Approach 1:
The patent introduces rare sugars with different chemical structures and metabolic pathways compared to conventional sugar substitutes. These rare sugars maintain sweetness while having negligible impact on flavor profile, thus achieving both caries prevention and minimal flavor impact simultaneously.
3Reliability
If alternative sugars are used to prevent dental caries, then caries prevention effect is improved, but effectiveness in suppressing acid generation deteriorates
Solution Approach 1:
The patent utilizes the unique metabolic parameter of rare sugars that cannot be efficiently metabolized by cariogenic bacteria such as Streptococcus mutans. This metabolic resistance prevents acid generation while maintaining caries prevention effectiveness, resolving the contradiction between overall caries prevention and specific acid generation suppression.
Data Source
AI summary
To provide a composition for preventing periodontal diseases (prophylactic agent of periodontal diseases), the composition having an excellent cariostatic property, being safe and stable for prolonged use and having less effects on flavor. A non-cariogenic material prepared by blending a rare sugar in the D form as selected from the group consisting of D-psicose, D-sorbose and D-tagatose, a rare sugar in the L form as selected from L-fructose, L-psicose and L-tagatose, or allitol as a rare sugar derivative, singly or in combination. A cariostatic agent comprising D-psicose, D-sorbose, D-tagatose, L-fructose, L-psicose and/or L-tagatose. A cariostatic agent in combination with catechins.