Ready-to-use indicator for medicament temperature control

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Solution Overview

Problem

Medication stored in cold environments can be painful to administer and requires precise temperature control for efficacy, necessitating a method to ensure the medicament reaches a suitable temperature for injection.

Innovation Solution

An injector system with a ready-to-use indicator that includes a pre-programmed timer, temperature sensor, and audio/visual alerts to notify users when the medicament has warmed to a safe injection temperature, utilizing a temperature analog to mimic the thermodynamic properties of the medicament and integrating these components into a reusable or disposable injection device.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If medicament is stored in cold environment to prevent spoilage, then medicament viability is maintained, but patient comfort deteriorates due to painful injection

Engineering Contradiction:
Improvemedicament viabilityVSAvoidinjection pain
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The system performs preliminary warming of the medicament by removing it from cold storage and allowing it to reach target temperature before injection. The ready-to-use indicator provides advance notification when the warming process is complete, enabling users to prepare in advance and avoid painful cold injections.

Inventive Principle:
Principle #10Preliminary action

2Object-affected harmful factors

If medicament is warmed to room temperature for comfortable injection, then patient comfort improves, but medicament may spoil or lose efficacy

Engineering Contradiction:
Improveinjection comfortVSAvoidmedicament efficacy
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The system carefully controls the temperature parameter of the medicament, warming it from cold storage temperature to a specific target temperature range that balances patient comfort with medicament stability. The controller monitors and adjusts heating to achieve the optimal temperature without overheating.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The temperature sensor provides continuous feedback to the controller about the medicament temperature. The controller uses this feedback to regulate the heating process and determine when the target temperature is reached, ensuring the medicament is warmed sufficiently for comfort but not overheated to the point of spoilage.

Inventive Principle:
Principle #23Feedback

3Measurement precision

If temperature monitoring system is added to track medicament temperature, then temperature control precision improves, but device complexity increases

Engineering Contradiction:
Improvetemperature control precisionVSAvoidinjector system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The temperature sensor, controller, and ready-to-use indicator are integrated into a single unified system within the injector. This merging of components achieves precise temperature monitoring and control without requiring separate complex systems for each function.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The system monitors its own temperature state automatically through the temperature sensor and controller, and self-regulates the heating process. The ready-to-use indicator provides automatic notification when heating is complete, eliminating the need for manual temperature checking by the user.

Inventive Principle:
Principle #25Self-service

4Productivity

If pre-programmed timer is used to track warming duration, then productivity improves by reducing waiting time uncertainty, but device complexity increases

Engineering Contradiction:
Improvewarming process efficiencyVSAvoidtimer mechanism complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The system pre-programs the timer with the expected warming duration based on typical conditions. When the injector is removed from cold storage, the timer automatically begins counting down, providing users with advance knowledge of when the medicament will be ready, allowing them to plan accordingly and improve workflow efficiency.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Ensures patient comfort by providing visual and audio cues when the medicament has reached a suitable temperature for injection, ensuring effective delivery while maintaining medicament viability.

Implementation Method 1

a temperature sensor may be in communication with the controller and configured to detect a temperature of the medicament or the temperature analog

Methodology Applied
Scientific EffectTemperature detection:

Implementation Method 2

a heating element may be in communication with the controller and configured to heat the medicament or the temperature analog

Methodology Applied
Scientific EffectHeating: Heating

Implementation Method 3

the controller may be configured to control the heating element... the temperature sensor may be in communication with the controller and configured to detect a temperature of the medicament or the temperature analog

Methodology Applied
Scientific EffectThermal feedback control: Feedback

Implementation Method 4

a ready-to-use indicator may be in communication with the controller and configured to provide a visual or audio notification when the medicament has reached the target temperature

Methodology Applied
Scientific EffectLED emission: Light Emitting Diode

Data Source

PatentEP3606579B1Injector with ready to use indicator
Publication Date: 2023.09.06 WEST PHARMACEUTICAL SERVICES INC
  • EP3606579B1 patent drawingFigure 1
  • EP3606579B1 patent drawingFigure 2
  • EP3606579B1 patent drawingFigure 3

AI summary

An injection system, including an injector having a dispensing mechanism configured to dispense a medicament, and a ready-to-use indicator. The ready-to-use indicator includes a controller configured to interact with the ready-to-use indicator and an audio and/or visual indicator, a temperature sensor, and a temperature analog having similar thermodynamic properties of the medicament. The temperature sensor is configured to detect a temperature of the temperature analog which represents the dynamic temperature of medicament as the medicament is heated or cooled. The temperature sensor is configured to communicate the detected temperature to the controller and to alert the controller when a preset temperature is reached. The ready-to-use indicator is configured to alert a user when the preset temperature is reached, signifying the medicament is thermally ready to be delivered by the dispensing mechanism. The audio and/or visual indicator is configured to display indicate one or more notifications to the user.