Reagent Storage Section for Continuous Sample Analysis

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing sample analyzers require multiple reagent containers of the same type to continue measurement when one becomes empty, and users cannot determine the optimal timing for reagent container replacement, leading to potential interruptions and inefficiencies.

Innovation Solution

A sample analyzer with a reagent storage section that allows continuous measurement by transferring reagents from a reagent container to the storage section, which then supplies the measurement section, and outputs messages for reagent replacement based on remaining amounts, enabling users to replenish reagents without interrupting the process.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If multiple reagent containers of the same type are connected to continue measurement when one becomes empty, then measurement continuity is improved, but device complexity increases

Engineering Contradiction:
Improvemeasurement continuityVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent introduces a reagent storage section as an intermediary component between the reagent container and the measurement section. This storage section temporarily holds reagent and enables continuous supply to the measurement section even when the reagent container is empty, thereby maintaining measurement continuity without requiring multiple reagent containers to be connected simultaneously

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The reagent supply system is segmented into distinct functional sections: the reagent container, the reagent storage section, and the measurement section. This segmentation allows the storage section to independently buffer reagent supply, decoupling the measurement continuity from the reagent container status and simplifying the overall system architecture

Inventive Principle:
Principle #1Segmentation

2Device complexity

If reagent container replacement timing is not indicated, then system operation is simplified, but loss of information occurs

Engineering Contradiction:
Improvesystem operationVSAvoidreplacement timing information
Core Design Contradiction:
Device complexityVSLoss of information

Solution Approach 1:

The patent implements a feedback mechanism where the system continuously monitors the reagent remaining amount in the reagent storage section and provides information to the user about the number of samples that can be measured without replacement. This feedback loop enables users to make informed decisions about replacement timing without adding complex operational procedures

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system automatically calculates and displays the number of measurable samples based on the remaining reagent amount, eliminating the need for users to manually track or calculate replacement timing. The system serves itself by providing this information autonomously, maintaining simple operation while preventing information loss

Inventive Principle:
Principle #25Self-service

3Loss of substance

If reagent transfer is suspended when storage section is low, then reagent wastage is prevented, but measurement interruption occurs

Engineering Contradiction:
Improvereagent wastageVSAvoidmeasurement continuity
Core Design Contradiction:
Loss of substanceVSReliability

Solution Approach 1:

The system performs preliminary actions by notifying the user in advance about the reagent remaining amount and the number of samples that can be measured. This early notification allows users to prepare for replacement before the storage section is depleted, preventing both reagent wastage and measurement interruptions through proactive planning

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables continuous sample measurement without the need for multiple reagent containers of the same type, allows timely reagent replenishment, and prevents wastage by suspending transfers before the storage section is empty, thus maintaining measurement integrity.

Implementation Method 1

a transfer unit that transfers the reagent from the reagent container to the reagent storage section and then from the reagent storage section to the measurement section

Methodology Applied
Scientific EffectFluid transfer:

Data Source

PatentEP2410340B1Sample analyzer
Publication Date: 2019.06.26 SYSMEX CORP
  • EP2410340B1 patent drawingFigure 1
  • EP2410340B1 patent drawingFigure 2
  • EP2410340B1 patent drawingFigure 3

AI summary

A sample analyzer is provided that does not require a plurality of reagent containers containing the same type of reagent to be connected, that can continue measurement even when a reagent container becomes empty, and that allows the timing of replacement of the reagent container to be recognized suitably. A reagent storage section is provided that is connected to a reagent container containing a reagent through a fluid channel and that stores the reagent transferred from the reagent container. A message for prompting replacement of the reagent container is outputted when it is detected that the remaining amount in the reagent container is a predetermined amount or less. A message for prompting to suspend sample measurement in the measurement section is outputted when it is detected that the remaining amount in the reagent storage section is a predetermined amount or less.