Reagent Vessel Tracking for Automatic Analyzers

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Solution Overview

Problem

Automatic analyzers face challenges in managing reagent degradation and efficient reagent usage, particularly when mixing reagents stored at cold and normal temperatures, leading to increased reagent consumption and operator workload due to frequent replacements and potential interruptions in analysis operations.

Innovation Solution

The implementation of a system that measures and manages the elapsed time of reagent vessels using a storage medium for reading reagent information, sets permissible placing limits, and transfers reagents between storage means to prevent degradation, minimize interruptions, and optimize reagent usage, including features like warning alerts and data alarms for expired reagents.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If a replacement reagent storing means without cold storage function is used, then operator workload is reduced and reagent replacement is simplified, but reagent degradation occurs over time

Engineering Contradiction:
Improvereagent replacement operationVSAvoidreagent stability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The system performs preliminary actions by reading reagent information from the storage medium when the reagent vessel is first loaded into the replacement storing means, and starts measuring the placing elapsed time at that point. This preliminary measurement and tracking enables proactive reagent management before degradation occurs.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The control unit continuously monitors the placing elapsed time and compares it against the permissible placing limit value stored in the system. When the elapsed time approaches or exceeds the limit, the system provides feedback through warnings or alarms, enabling timely reagent replacement or transfer to cold storage.

Inventive Principle:
Principle #23Feedback

2Productivity

If reagent vessels are kept in replacement storing means for long periods, then operator intervention is minimized, but reagent degradation increases

Engineering Contradiction:
Improveanalysis throughputVSAvoidreagent degradation
Core Design Contradiction:
ProductivityVSLoss of substance

Solution Approach 1:

The control unit continuously monitors the placing elapsed time and compares it against the permissible placing limit value. When the limit is reached or exceeded, the system provides feedback through warnings or alarms, enabling timely reagent replacement or transfer to cold storage, thus preventing degradation while maintaining continuous operation.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system automatically tracks and manages reagent vessels themselves by reading information from their storage media and monitoring their placement time. This self-service capability eliminates the need for manual tracking while ensuring reagents are replaced before degradation occurs.

Inventive Principle:
Principle #25Self-service

3Reliability

If permissible placing limit values are enforced strictly, then reagent quality is maintained, but analysis operations may be interrupted

Engineering Contradiction:
Improvereagent qualityVSAvoidanalysis continuity
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The system performs preliminary actions by tracking the placing elapsed time from the moment the reagent vessel is loaded. This continuous monitoring enables proactive scheduling of reagent transfers or replacements before the permissible limit is reached, allowing operations to be planned and executed during appropriate intervals without disrupting analysis continuity.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentEP2647998B1Automatic analytical apparatus
Publication Date: 2021.06.02 HITACHI HIGH TECH CORP
  • EP2647998B1 patent drawingFigure 1
  • EP2647998B1 patent drawingFigure 2

AI summary

Unlike conventional reagent storing means of an analyzing unit having a cold-storage function, replacement reagent storing means having no cold-storage function requires reagent management of a higher order. An automatic analyzer is provided that manages the placing elapsed time for a reagent vessel in replacement reagent storing means 2, compares the placing elapsed time for the reagent with a permissible placing limit value stored as one of analysis parameters for each analysis item, and determines as to whether or not the placing elapsed time exceeds permissible limit value. In this way, the analyzer prevents the degradation of the reagent and automatically transfers the reagent to an analyzing section for performing measurement.