Reciprocating Cannula Tissue Resection for Sterile Core Preservation
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Solution Overview
Problem
Existing tissue removal devices cause damage to both the resected tissue and surrounding tissues due to traction, ablative energy, and thermal effects, compromising the integrity and viability of the tissue for personalized medicine applications, and lack the ability to maintain a sterile environment during transport.
Innovation Solution
A tissue cutting device with a reciprocating inner cannula within an outer cannula, configured to minimize crush artifact and thermal damage, accompanied by a fluid supply sleeve for maintaining a sterile environment and preserving tissue integrity during transport.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If ablative or thermal energy is used to remove tissue, then tissue removal efficiency is improved, but tissue integrity and viability are damaged
Solution Approach 1:
The patent replaces ablative and thermal energy systems with a mechanical cutting system consisting of a reciprocating inner cannula with a cutting edge that physically severs tissue through controlled mechanical motion, eliminating thermal damage while maintaining efficient tissue removal
Solution Approach 2:
The patent extracts the harmful thermal and ablative energy components from the tissue removal system, retaining only the essential mechanical cutting function through a dedicated cutting edge on the inner cannula, thereby separating the useful cutting action from the harmful thermal effects
2Productivity
If traction is applied to remove tissue, then tissue removal is achieved, but surrounding collateral tissue is damaged
Solution Approach 1:
The patent removes the traction mechanism entirely from the system, replacing it with a direct mechanical cutting action at the tissue site, thereby eliminating the harmful pulling forces that damage surrounding collateral tissue while maintaining effective tissue removal
Solution Approach 2:
The cutting edge on the inner cannula serves as an intermediary that directly severs tissue at the point of contact, eliminating the need for traction forces that would otherwise be transmitted through and damage surrounding healthy tissue
3Ease of operation
If resected tissue is transported outside sterile environment, then transport convenience is improved, but tissue sterility is compromised
Solution Approach 1:
The patent nests the tissue collector within the sterile surgical instrument housing, allowing the collector to be sterilized alongside the instrument and remain within the sterile field throughout the procedure, thereby maintaining tissue sterility while enabling convenient collection and transport
Solution Approach 2:
The patent merges the tissue collector with the sterile surgical instrument system, creating an integrated assembly that maintains sterility throughout the procedure, thereby combining the benefits of convenient tissue collection with the requirement for sterile transport
4Productivity
If rapid tissue debulking is performed, then productivity is improved, but control over delicate structures is reduced
Solution Approach 1:
The patent employs a dynamic reciprocating motion of the inner cannula that can be controlled in speed and amplitude, allowing rapid cutting for debulking when needed while enabling precise, slow movements when working near delicate structures, thereby adapting the system's operational characteristics to the specific surgical requirements
Data Source
AI summary
A tissue cutting device that is especially suited for neurosurgical applications is disclosed and described, as well as alternative systems for tissue preservation and transport. The cutting device includes an outer cannula in which a reciprocating inner cannula is disposed. A tissue collector is also provided and is in fluid communication with the lumen of the inner cannula. A temperature control sleeve may be disposed around the tissue collector to control the temperature of the tissue samples. A preservation system may be supplied that is configured to deliver fluids to tissue samples in the tissue collector. A fluid supply sleeve may be disposed about the outer cannula and is selectively positionable along the length of the outer cannula.