Reciprocating Tissue Cutter With Focused Charge Delivery

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Solution Overview

Problem

Existing transcatheter procedures for treating left ventricular outflow tract (LVOT) obstruction, such as those described in PCT/US2023/060223, are limited by the need for forming a passageway through tissue and then cutting above it, which can be inefficient and may cause unwanted tissue damage.

Innovation Solution

A catheter-based system with a reciprocating cutter that cuts from the outer surface of the obstruction downwardly into the tissue, using an insulation-modified guidewire with an asymmetric insulation gap to concentrate electrical charge and minimize bystander injury, and includes a guidewire with a tissue anchor to facilitate precise cutting.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If a guidewire is used to traverse obstructive heart valve leaflet tissue and electrified during traction, then longitudinal split of the leaflet is accomplished, but the kinked guidewire concentrates electrical charge on the outer aspect of the kink causing potential bystander injury

Engineering Contradiction:
Improvecutting precisionVSAvoidbystander injury
Core Design Contradiction:
Manufacturing precisionVSObject-affected harmful factors

Solution Approach 1:

The patent applies asymmetry by positioning the insulation gap at a specific location on the guidewire rather than uniformly insulating the entire wire. The insulation gap is placed strategically to control where electrical charge concentrates during electrosurgery, directing it toward the target tissue while preventing concentration on the outer aspect of the kink that would cause bystander injury. This asymmetric insulation design resolves the contradiction by maintaining cutting precision while eliminating harmful electrical charge concentration.

Inventive Principle:
Principle #4Asymmetry

2Manufacturing precision

If an insulation-modified guidewire is used to concentrate electrical charge at the therapy target, then cutting precision is improved, but the complexity of the device increases

Engineering Contradiction:
Improvecharge delivery precisionVSAvoidguidewire structure
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent applies local quality by modifying only a specific portion of the guidewire with an insulation gap rather than changing the entire wire structure. The insulation gap is localized to the region where precise charge delivery is needed, while the rest of the guidewire maintains its standard simple structure. This approach achieves improved charge delivery precision at the therapy target without significantly increasing overall device complexity.

Inventive Principle:
Principle #3Local quality

3Ease of operation

If a reciprocating cutter is used to cut from the outer surface downwardly into the tissue, then procedural control is enhanced, but the device complexity increases

Engineering Contradiction:
Improveprocedural controlVSAvoidcatheter system
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The patent applies dynamics by implementing a reciprocating cutter that moves back and forth in a controlled oscillating motion rather than a static or single-action cutting mechanism. This dynamic reciprocating motion allows the cutter to progressively penetrate the tissue from the outer surface downwardly, providing enhanced procedural control through adjustable cutting depth and speed. The dynamic nature of the reciprocating mechanism enables better control over the cutting process while the overall device complexity is managed through efficient mechanical design.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively cuts through myocardial tissue with reduced risk of collateral damage, enhancing procedural control and success rates for treating LVOT obstruction.

Implementation Method 1

The kink or bend concentrates electrical charge and helps to position the charge-delivery-device at the therapy target to avoid bystander injury.

Methodology Applied
Scientific EffectElectrical charge concentration: Electric Field

Implementation Method 2

The electrically conductive element is configured to be coupled to an electrical power source in order to electrify the electrically conductive element

Methodology Applied
Scientific EffectJoule heating: Joule Heating

Implementation Method 3

relative longitudinal movement of the elongate tether and the elongate body causes the cutting element to cut through anatomical tissue that the device is placed adjacent to

Methodology Applied
Scientific EffectMechanical cutting: Mechanical Force

Data Source

PatentUS12496126B2Tissue cutting systems and methods
Publication Date: 2025.12.16 TRANSMURAL SYSTEMS LLC
  • US12496126B2 patent drawing
  • US12496126B2 patent drawing
  • US12496126B2 patent drawing

AI summary

The disclosure provides various embodiments of systems to facilitate the cutting of tissue structures and other tissue structures percutaneously.