Reciprocating Tissue Cutter With Focused Charge Delivery
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Solution Overview
Problem
Existing transcatheter procedures for treating left ventricular outflow tract (LVOT) obstruction, such as those described in PCT/US2023/060223, are limited by the need for forming a passageway through tissue and then cutting above it, which can be inefficient and may cause unwanted tissue damage.
Innovation Solution
A catheter-based system with a reciprocating cutter that cuts from the outer surface of the obstruction downwardly into the tissue, using an insulation-modified guidewire with an asymmetric insulation gap to concentrate electrical charge and minimize bystander injury, and includes a guidewire with a tissue anchor to facilitate precise cutting.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If a guidewire is used to traverse obstructive heart valve leaflet tissue and electrified during traction, then longitudinal split of the leaflet is accomplished, but the kinked guidewire concentrates electrical charge on the outer aspect of the kink causing potential bystander injury
Solution Approach 1:
The patent applies asymmetry by positioning the insulation gap at a specific location on the guidewire rather than uniformly insulating the entire wire. The insulation gap is placed strategically to control where electrical charge concentrates during electrosurgery, directing it toward the target tissue while preventing concentration on the outer aspect of the kink that would cause bystander injury. This asymmetric insulation design resolves the contradiction by maintaining cutting precision while eliminating harmful electrical charge concentration.
2Manufacturing precision
If an insulation-modified guidewire is used to concentrate electrical charge at the therapy target, then cutting precision is improved, but the complexity of the device increases
Solution Approach 1:
The patent applies local quality by modifying only a specific portion of the guidewire with an insulation gap rather than changing the entire wire structure. The insulation gap is localized to the region where precise charge delivery is needed, while the rest of the guidewire maintains its standard simple structure. This approach achieves improved charge delivery precision at the therapy target without significantly increasing overall device complexity.
3Ease of operation
If a reciprocating cutter is used to cut from the outer surface downwardly into the tissue, then procedural control is enhanced, but the device complexity increases
Solution Approach 1:
The patent applies dynamics by implementing a reciprocating cutter that moves back and forth in a controlled oscillating motion rather than a static or single-action cutting mechanism. This dynamic reciprocating motion allows the cutter to progressively penetrate the tissue from the outer surface downwardly, providing enhanced procedural control through adjustable cutting depth and speed. The dynamic nature of the reciprocating mechanism enables better control over the cutting process while the overall device complexity is managed through efficient mechanical design.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system effectively cuts through myocardial tissue with reduced risk of collateral damage, enhancing procedural control and success rates for treating LVOT obstruction.
Implementation Method 1
The kink or bend concentrates electrical charge and helps to position the charge-delivery-device at the therapy target to avoid bystander injury.
Implementation Method 2
The electrically conductive element is configured to be coupled to an electrical power source in order to electrify the electrically conductive element
Implementation Method 3
relative longitudinal movement of the elongate tether and the elongate body causes the cutting element to cut through anatomical tissue that the device is placed adjacent to
Data Source
AI summary
The disclosure provides various embodiments of systems to facilitate the cutting of tissue structures and other tissue structures percutaneously.


