Recombinant Myoglobin Supplement for Better Iron Absorption
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Solution Overview
Problem
Existing iron supplements, such as ferrous fumarate, ferrous gluconate, and ferrous sulfate, are associated with side effects like nausea and inefficient absorption, and can interfere with other medications, while many individuals do not get adequate iron from their diet, leading to iron deficiency and related disorders.
Innovation Solution
A nutritional supplement comprising recombinant myoglobin derived from genetically modified microorganisms, which provides a bioavailable source of iron through microbial fermentation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If conventional iron supplements (ferrous fumarate, ferrous gluconate, ferrous sulfate) are used, then iron supplementation is provided, but side effects such as nausea and inefficient absorption occur
Solution Approach 1:
The patent uses myoglobin as an intermediary carrier to deliver iron to the body. Instead of administering iron directly in its conventional salt forms (which cause nausea and poor absorption), the iron is bound within the myoglobin protein structure. This intermediary approach allows iron to be transported and absorbed more efficiently while reducing harmful side effects, as the protein matrix protects the iron and facilitates its uptake by human cells.
Solution Approach 2:
The patent changes the chemical form and physical state of iron from conventional inorganic salts to organic iron bound within a protein structure. By altering iron's molecular environment from simple salts to a complex protein-bound state, the bioavailability and tolerability of iron are improved, transforming it from a poorly absorbed supplement into a more effective and gentler nutritional supplement.
2Quantity of substance
If conventional iron supplements are used, then iron is provided, but absorption of other medications decreases due to insoluble complex formation
Solution Approach 1:
Myoglobin serves as a protective intermediary that prevents iron from directly interacting with other medications. The protein structure encapsulates the iron, preventing it from forming insoluble complexes with drugs like methyldopa/levodopa, fluoroquinolones, penicillin, or tetracyclines. This intermediary barrier allows iron supplementation without interfering with the absorption of concurrent medications.
3Stability of the object's composition
If dietary iron sources are relied upon, then natural nutrition is maintained, but adequate iron intake is not achieved for certain groups
Solution Approach 1:
The patent creates a composite nutritional supplement that combines the benefits of natural protein (myoglobin) with essential mineral (iron). Rather than relying solely on dietary sources that may be insufficient for certain populations, this composite material provides a concentrated, bioavailable form of iron within a natural protein matrix, ensuring adequate iron intake while maintaining natural nutritional principles.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The supplement enhances iron absorption and reduces side effects, improving overall health and well-being by providing a bioavailable iron source, particularly beneficial for individuals at risk of iron deficiency or related disorders.
Implementation Method 1
the myoglobin is obtained from fermentation by a microorganism which has been genetically modified to express the recombinant myoglobin
Data Source
AI summary
This invention relates to a nutritional supplement comprising a myoglobin and a method for preparing said nutritional supplement comprising a myoglobin, wherein the myoglobin may be a myoglobin obtained from fermentation by a microorganism.