Reconstructing Surface ECG from Endocardial Far Field Signals
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Solution Overview
Problem
Existing methods for reconstructing surface electrocardiogram (ECG) signals from endocardial or epicardial electrogram (EGM) signals face challenges such as precision loss due to neglecting propagation time delays and varying lead positions, leading to inaccurate diagnoses, especially in irregular heart rhythms, and lack a quality assessment criterion for reconstruction quality.
Innovation Solution
A device and method that extract ventricular and atrial far field signal components from EGM signals, using near field estimator filters and adaptive filtering algorithms to reconstruct multiple ECG signals with improved accuracy, and includes a quality assessment mechanism using correlation coefficients to validate filter parameters and ensure reconstruction quality.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Device complexity
If ECG reconstruction is performed using simple linear combination of EGM signals, then device complexity is reduced, but measurement precision deteriorates due to neglecting propagation time delays
Solution Approach 1:
The patent applies preliminary action by pre-calculating and storing transfer matrices during a learning phase that captures propagation time delays and lead position variations. These pre-computed matrices are then reused during actual ECG reconstruction, avoiding real-time complex calculations while maintaining high accuracy. The learning phase stores the relationship between EGM and ECG signals in different conditions, enabling accurate reconstruction without real-time computational burden.
Solution Approach 2:
The patent changes parameters by using adaptive transfer matrices that are updated based on detected lead positions and patient-specific characteristics. The system adjusts the reconstruction parameters (transfer matrices) according to varying conditions such as lead displacement or changes in body geometry, thereby maintaining measurement precision without requiring complex real-time computation. This allows the system to adapt to different physiological states while using computationally efficient methods.
2Measurement precision
If ECG reconstruction accounts for propagation time delays and lead position variations, then measurement precision is improved, but device complexity increases
Solution Approach 1:
The patent pre-computes transfer matrices during a learning phase that captures propagation time delays and lead position variations. These pre-calculated matrices are stored and reused during actual ECG reconstruction, eliminating the need for complex real-time calculations. The system performs the computationally intensive work in advance, when accuracy is critical but computational resources can be dedicated to learning rather than real-time processing.
Solution Approach 2:
The patent creates simplified copies of the complex physiological propagation processes by using pre-computed transfer matrices that model the relationship between EGM and ECG signals. Instead of simulating the actual complex electrical propagation through tissues in real-time, the system uses copied relationships from the learning phase, which capture the essential characteristics without requiring complex computational models during operation.
3Measurement precision
If surface electrodes are placed for ECG recording during routine visits, then measurement precision is improved, but ease of operation deteriorates due to preparation time and patient discomfort
Solution Approach 1:
The patent extracts the ECG signal acquisition function from the complex process of surface electrode placement and Holter recorder usage. By utilizing the already-implanted device's electrodes and processing capabilities, the system eliminates the need for external ECG recording equipment and preparation procedures. The implantable device itself performs ECG reconstruction from its existing EGM signals, removing the separate ECG recording step entirely.
Solution Approach 2:
The patent makes the implantable device universal by enabling it to perform multiple functions: its original pacing/defibrillation function plus ECG reconstruction and monitoring. The same implanted electrodes and processing unit that were designed for cardiac therapy are now also used for ECG signal acquisition and reconstruction, eliminating the need for separate ECG recording equipment and simplifying the overall system.
4Measurement precision
If ECG recording is performed with surface electrodes, then measurement precision is improved, but loss of time increases due to patient preparation and visit scheduling
Solution Approach 1:
The patent enables the implantable device to perform ECG reconstruction autonomously using its own embedded processing capabilities. The device automatically reconstructs ECG signals from its EGM measurements without requiring external equipment or practitioner intervention for signal acquisition. This self-service capability allows continuous or frequent monitoring without scheduling constraints, eliminating the time loss associated with arranging and performing scheduled ECG recordings.
Solution Approach 2:
The patent extracts the ECG recording function from the time-consuming process of scheduled clinic visits with surface electrode placement. By using the implantable device's existing sensors and processing unit, the system performs ECG reconstruction at the patient's home or in routine device checks, removing the need for dedicated ECG recording appointments and significantly reducing the time intervals between effective monitoring opportunities.
Data Source
AI summary
Reconstruction of a surface electrocardiogram from far field signals extracted from an endocardial electrogram in an active medical device is disclosed. The device collects a ventricular EGM signal (EGMV) and an atrial EGM signal (EGMA), and extracts a ventricular far field signal component (FFV) and an atrial far field signal component (FFA). The ventricular and atrial far field signal components are combined to deliver as an output a reconstructed surface electrogram ECG signal (ECGj*). The ventricular and atrial far field signals are respectively extracted from the collected ventricular and atrial EGM signals (FFV, FFA). The reconstruction of the ECG is operated by ventricular (18) and atrial (16) far field signal estimator filters. According to one embodiment, the far field signal estimator filters are linear or nonlinear filters, receiving as input the far field signal components. An adder (20) adds the filtered signals and delivers as output the reconstructed ECG signal (ECGj*).


