Red Clover Pomegranate Extract for Menopause Relief

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Solution Overview

Problem

Current treatments for menopausal symptoms, such as hormone therapy, come with adverse effects, and there is a need for a natural composition that effectively relieves these symptoms without such drawbacks.

Innovation Solution

A composite extract of pomegranate and red clover is used as an active ingredient in a composition for reducing menopausal disorders, administered through various routes, including pharmaceutical, food, and cosmetic forms, to provide synergistic relief without adverse effects.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If hormone therapy is used to supplement declining female hormones, then menopausal symptoms are relieved, but adverse effects such as uterus cancer, breast cancer, stroke and pulmonary embolism occur

Engineering Contradiction:
Improveeffectiveness in relieving menopausal symptomsVSAvoidadverse effects including cancer and stroke
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces long-term hormone therapy with a natural plant extract composition that provides temporary but effective relief through phytoestrogens, avoiding the cumulative adverse effects of prolonged synthetic hormone use

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent combines multiple plant extracts (red clover, pomegranate, and other natural sources) to create a composite composition that synergistically provides estrogen-like effects while minimizing side effects through the diversity of phytochemical compounds

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If phytoestrogens are used to provide weak estrogen-like effects, then adverse effects are reduced, but the effectiveness compared to hormone therapy is reduced

Engineering Contradiction:
Improveadverse effects of hormone therapyVSAvoideffectiveness in relieving menopausal symptoms
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent combines multiple phytoestrogen sources (red clover extract, pomegranate extract, and other plant extracts) to merge their individual weak effects into a synergistic composition that achieves therapeutic effectiveness comparable to hormone therapy while maintaining the safety profile of natural compounds

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent optimizes the concentration ratios and extraction parameters of different plant components to maximize the bioavailability and effectiveness of phytoestrogens, transforming them from weak individual agents into a potent combined therapy

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The pomegranate and red clover composite extract effectively alleviates menopausal symptoms, including osteoporosis inhibition and uterus protection, with a synergistic effect that surpasses individual extracts, offering relief with minimal side effects.

Implementation Method 1

Phytoestrogens are structurally similar to estrogen so that they can bind to estrogen receptor ER-alpha and ER-beta, showing a weak estrogen-like effect

Methodology Applied
Scientific EffectPhytoestrogen binding to estrogen receptor:

Data Source

PatentUS10709750B2Female menopause alleviation use of composition containing composite extract of red clover and pomegranate as active ingredient
Publication Date: 2020.07.14 HLSCIENCE CO LTD
  • US10709750B2 patent drawing
  • US10709750B2 patent drawing
  • US10709750B2 patent drawing

AI summary

The present invention relates to: a natural composition containing a composite extract of pomegranates and red clover, exhibiting synergistic effects with respect to a menopausal symptom alleviation effect, an estrogen-like effect, an anti-obesity effect, a hyperlipidemia inhibitory effect, a fatty liver protective effect, an osteoporosis inhibitory effect and the like without any side effects; and various uses thereof, in particular, pharmaceutical, bromatological and cosmetic uses.