Red Ginseng Hydrolysis Concentrate Bitterness Reduction

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Solution Overview

Problem

Current methods for producing red ginseng hydrolysis concentrate with high compound K content are inefficient, leading to ginsenoside loss and bitterness in the final product, making it difficult to achieve a high-quality concentrate with enhanced pharmacological effects and palatability.

Innovation Solution

A process involving the extraction of red ginseng with specific plant extracts, followed by an enzyme reaction using beta-glucosidase and pectinase, and subsequent centrifugation under reduced pressure to minimize ginsenoside loss and enhance compound K conversion, while reducing bitterness.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If conventional enzymatic processes are used to convert ginsenosides to compound K, then compound K content can be increased, but ginsenoside loss and bitterness occur, reducing product quality

Engineering Contradiction:
Improvecompound K contentVSAvoidginsenoside loss
Core Design Contradiction:
Quantity of substanceVSLoss of substance

Solution Approach 1:

The patent applies preliminary action by performing extraction of red ginseng with specific plant extracts (bamboo shoot, Japanese gerbera leaf, oriental arbor vitae fruit, and false daisy) before the enzymatic conversion process. This preliminary extraction step removes bitterness and prepares the ginseng matrix for efficient enzyme-mediated conversion of ginsenosides to compound K, thereby preventing ginsenoside loss while enhancing compound K content.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses an intermediary approach by introducing specific plant extracts as mediators in the extraction process. These plant extracts (bamboo shoot, Japanese gerbera leaf, oriental arbor vitae fruit, and false daisy) act as intermediaries that facilitate the conversion of ginsenosides to compound K while simultaneously removing bitterness, thus resolving the contradiction between increasing compound K content and preventing ginsenoside loss.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If conventional extraction methods are used to produce red ginseng concentrate, then production efficiency can be maintained, but the final product contains bitterness and lacks enhanced pharmacological effects

Engineering Contradiction:
Improveproduction efficiencyVSAvoidbitterness
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The patent merges multiple functions into a single integrated process. The extraction of red ginseng is combined with the enzymatic conversion of ginsenosides to compound K and the removal of bitterness in one unified process using specific plant extracts. This merging approach maintains production efficiency while simultaneously eliminating bitterness and enhancing pharmacological effects through the synergistic action of the plant extract components.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent employs composite materials by using a combination of specific plant extracts (bamboo shoot, Japanese gerbera leaf, oriental arbor vitae fruit, and false daisy) as a composite extraction medium. This composite material approach enables simultaneous achievement of bitterness removal, efficient ginsenoside extraction, and promotion of compound K formation, thereby maintaining productivity while improving product quality.

Inventive Principle:
Principle #40Composite materials

3Quantity of substance

If enzyme reaction is carried out to convert ginsenosides to compound K, then compound K content increases, but the process complexity and time requirements increase

Engineering Contradiction:
Improvecompound K contentVSAvoidprocess time
Core Design Contradiction:
Quantity of substanceVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-treating the red ginseng with specific plant extracts before the enzymatic conversion. This preliminary extraction step prepares the ginseng matrix to be more receptive to enzymatic conversion, thereby reducing the time required for the subsequent enzyme reaction to achieve high compound K content.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent utilizes parameter changes by optimizing the extraction conditions (temperature, time, extract concentration) and enzyme reaction parameters (enzyme type, temperature, pH) to achieve efficient conversion. By carefully controlling these parameters, the process achieves high compound K content while minimizing total process time through optimized condition settings.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The process effectively increases the concentration of compound K in red ginseng hydrolysis concentrate, minimizing ginsenoside loss and improving the taste by reducing bitterness, resulting in a high-quality, easily consumable product with enhanced pharmacological effects.

Implementation Method 1

adding an enzyme solution comprising beta-glucosidase and pectinase to the red ginseng concentrate prepared in the above step (5) to have an enzyme reaction

Methodology Applied
Scientific EffectEnzyme catalysis: Enzyme

Implementation Method 2

a technique for converting ginsenosides contained in ginseng to compound K by using enzyme or radiation has been developed

Methodology Applied
Scientific EffectHydrolysis: Hydrolysis

Implementation Method 3

centrifuging the mixture solution of red ginseng and alcohol prepared in the above step (6) followed by concentration under reduced pressure of a supernatant separated by the centrifuge

Methodology Applied
Scientific EffectCentrifugal separation: Centrifugal Separation

Implementation Method 4

concentration under reduced pressure of a supernatant separated by the centrifuge

Methodology Applied
Scientific EffectEvaporation under reduced pressure: Evaporation

Data Source

PatentEP4094770B1Process for production of red ginseng hydrolysis concentrate having enriched specific component
Publication Date: 2024.11.20 DAEDONG KOREA GINSENG CO LTD
  • EP4094770B1 patent drawing

AI summary

The present invention relates to a process for production of red ginseng hydrolysis concentrate comprising: carrying out an enzyme reaction of red ginseng concentrate by adding an enzyme solution followed by addition of alcohol to prepare a mixture solution of red ginseng and alcohol; and centrifuging the prepared mixture solution of red ginseng and alcohol followed by concentration under reduced pressure of a supernatant separated by the centrifuge, and a red ginseng hydrolysis concentrate produced by the aforementioned process.