Reference Image Selection for Accurate Contrast Bolus MRI Triggering

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Solution Overview

Problem

Current MRI systems face challenges in accurately timing contrast-enhanced scans due to operator-dependent methods for initiating post-contrast acquisitions, which can lead to inadvertent timing errors and missed scans, especially when subjects exhibit unusual contrast kinetics.

Innovation Solution

A scan interface that combines live 2D images and an automatically-generated contrast plot in a single view, allowing for operator-initiated and auto-triggered scan initiation, with adjustable ROI settings, to improve timing accuracy and reduce cognitive load.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If operator-dependent methods are used to initiate post-contrast acquisitions, then flexibility in scan initiation is maintained, but timing accuracy deteriorates due to inadvertent timing errors and missed scans

Engineering Contradiction:
Improvetiming accuracyVSAvoidoperator dependency
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The system automatically detects contrast bolus arrival using image processing algorithms and triggers post-contrast acquisitions without operator intervention. The processing system monitors contrast agent concentration in real-time and autonomously initiates scanning when threshold criteria are met, eliminating timing errors caused by operator dependency while maintaining scan quality through automated precision.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system continuously monitors contrast agent concentration in real-time using image processing and provides feedback to automatically trigger post-contrast acquisitions when predetermined criteria are met. This closed-loop feedback mechanism ensures accurate timing by adapting to actual contrast kinetics rather than relying on operator estimation, thereby improving timing precision while reducing operational complexity.

Inventive Principle:
Principle #23Feedback

2Measurement precision

If automated contrast plot generation is implemented, then timing accuracy is improved, but device complexity increases

Engineering Contradiction:
Improvetiming accuracyVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The processing system performs multiple functions including contrast plot generation, bolus arrival detection, and automatic scan triggering using a unified algorithmic framework. By consolidating these functions into a single multi-functional processing pipeline rather than separate systems, the patent improves timing accuracy through automated contrast monitoring while minimizing the increase in overall system complexity through functional integration.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Productivity

If real-time visualization and automated triggers are combined, then scan efficiency is enhanced, but measurement precision requirements increase

Engineering Contradiction:
Improvescan efficiencyVSAvoidcontrast detection precision
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system pre-establishes predetermined criteria for bolus arrival detection and contrast thresholds before scanning begins. These pre-set parameters enable real-time automated triggering without requiring complex real-time decision-making, thereby enhancing scan efficiency through rapid automated response while maintaining measurement precision through predefined, validated detection criteria that ensure accurate contrast bolus identification.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20250384555A1System and method for selection of reference images for use in detecting and tracking arrival of contrast bolus in contrast-enhanced magnetic resonance imaging
Publication Date: 2025.12.18 GE PRECISION HEALTHCARE LLC
  • US20250384555A1 patent drawing
  • US20250384555A1 patent drawing
  • US20250384555A1 patent drawing

AI summary

For a given MR image having an anatomical landmark and a frame of reference, a method includes automatically selecting one or more series of MR images from a plurality of series of MR images previously acquired and having the anatomical landmark and the frame of reference. The method includes automatically selecting one or more candidate groups from the one or more series of MR images that were selected, wherein selection of the one or more candidate groups is based on predetermined rules. The method includes automatically selecting a respective reference image from each candidate group, wherein selection of each respective reference image is based on the predetermined rules. The method further includes automatically displaying the respective reference image selected for each candidate group, wherein each respective reference image is displayed in reference viewports on a user interface on a display based on the predetermined rules.