Regional Oximetry Signal Processing for Motion and Crosstalk

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Solution Overview

Problem

Conventional pulse oximetry systems fail to accurately measure oxygen saturation during patient motion, low perfusion, intense light interference, and electrosurgical instrument interference, and do not account for venous blood movement, leading to errors in arterial oxygen saturation readings.

Innovation Solution

Regional oximetry systems utilize dual sensors with synchronized emitter modulation to minimize crosstalk and a signal processing pod that includes a digital signal processor (DSP) to derive regional oxygen saturation parameters, capable of operating under challenging conditions and integrating with various monitors via USB.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional pulse oximetry is used, then the system is simple and easy to operate, but it fails to accurately measure oxygen saturation during patient motion and under challenging conditions

Engineering Contradiction:
Improveaccuracy of oxygen saturation measurementVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system segments the optical measurement into multiple independent channels with different wavelength combinations (e.g., red LED at 660nm, infrared LED at 940nm, and green LED at 530nm). Each channel processes signals independently through dedicated photodetectors and amplifiers, allowing the system to handle complex interference patterns by analyzing multiple wavelength responses simultaneously, thereby improving reliability without requiring a completely new measurement approach

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system introduces an intermediary signal processing layer that includes motion detectors, ambient light sensors, and electrosurgical interference detectors. These intermediary components detect and characterize interference signals before they affect the final oxygen saturation calculation, allowing the system to compensate for motion artifacts, ambient light variations, and ESU interference through algorithmic correction rather than physical isolation

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If advanced pulse oximetry processes venous blood signals, then true arterial oxygen saturation can be measured during motion, but the system complexity increases

Engineering Contradiction:
Improveprecision of arterial oxygen saturationVSAvoidsignal processing complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system employs periodic modulation of LED emitters at specific frequencies (e.g., 1kHz for red LED, 1.2kHz for infrared LED, 1.5kHz for green LED) to create time-resolved optical signals. This periodic action allows the system to distinguish between pulsatile arterial blood flow and non-pulsatile venous blood flow through frequency filtering, enabling precise arterial oxygen saturation measurement while managing processing complexity through structured temporal patterns

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The system implements feedback mechanisms where motion detectors continuously monitor for patient movement and adjust signal processing parameters in real-time. When motion artifacts are detected, the system automatically adjusts the weightings of different wavelength channels and modifies the pulse oximetry algorithm to compensate for the specific type and magnitude of motion interference, maintaining measurement precision through adaptive feedback control

Inventive Principle:
Principle #23Feedback

3Measurement precision

If dual sensors with synchronized emitter modulation are used, then crosstalk is minimized and regional oxygen saturation is accurately measured, but device complexity increases

Engineering Contradiction:
Improveaccuracy of regional oxygen saturationVSAvoidsensor and signal processing complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system modulates multiple LED emitters at different frequencies within a synchronized periodic framework. The first LED emitter operates at a first frequency while the second LED emitter operates at a second frequency, with both frequencies locked to a common reference clock. This synchronized periodic modulation enables the system to resolve signals from multiple sensors and wavelength combinations without crosstalk, achieving precise regional oxygen saturation measurement through frequency-domain separation

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The system uses identical sensor architectures replicated at multiple locations (e.g., forehead sensors, forearm sensors, chest sensors) with the same emitter-detector configuration. Each sensor location contains copies of the core optical measurement circuitry, allowing the system to measure oxygen saturation at multiple regional sites simultaneously using standardized processing algorithms, thereby reducing overall system complexity through modular replication

Inventive Principle:
Principle #26Copying

4Adaptability or versatility

If regional oximetry monitoring is implemented, then regional hypoxemia can be detected, but the system integrates multiple components increasing complexity

Engineering Contradiction:
Improveability to detect regional hypoxemiaVSAvoidsystem integration complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system employs a universal signal processing platform that can handle multiple sensor types, wavelength combinations, and monitoring locations through a single integrated architecture. The same core processing circuitry and software algorithms serve forehead sensors, forearm sensors, chest sensors, and other regional monitoring sites, allowing the system to detect regional hypoxemia at any location without requiring location-specific dedicated processing hardware, thereby managing integration complexity through multi-functionality

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides accurate regional oxygen saturation measurements, automating differential analysis and detecting regional hypoxemia, while maintaining performance during patient motion and interference, and integrating with a range of monitoring devices.

Implementation Method 1

A typical pulse oximetry system utilizes an optical sensor attached to a fingertip to measure the relative volume of oxygenated hemoglobin in pulsatile arterial blood flowing within the fingertip

Methodology Applied
Scientific EffectOptical transmission: Light

Implementation Method 2

Regional oximetry systems utilize dual sensors with synchronized emitter modulation to minimize crosstalk

Methodology Applied
Scientific EffectSignal modulation: Phase Modulation

Data Source

PatentUS12357237B1Regional oximetry signal processor
Publication Date: 2025.07.15 MASIMO CORP
  • US12357237B1 patent drawing
  • US12357237B1 patent drawing
  • US12357237B1 patent drawing

AI summary

A regional oximetry system comprises a pod having a pod housing defining a sensor end and an opposite monitor end. A dual sensor connector is in electrical communication with the sensor end of the pod housing. A monitor connector is in electrical communication with the monitor end of the pod housing. An analog board is disposed within the pod housing and is in electrical communications with the dual sensor connector. The analog board receives and digitizes sensor signals from at least one optical sensor plugged into the dual sensor connector. A digital board is disposed within the pod housing and in electrical communications with the analog board and the monitor connector. A digital signal processor (DSP) is mounted on the digital board and implements a regional oximetry signal processor so as to receive digitized sensor signals from the analog board, derive regional oximetry parameters from the digitized sensor signals and communicate the regional oximetry parameters to the monitor connector for display on an attached monitor.