Remote Cryogenic Sample Processing System for Multi-Site Monitoring
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Solution Overview
Problem
Current cryogenic processing systems lack effective remote monitoring capabilities, leading to potential errors in freezing, storage, and transportation of samples, which are critical for maintaining sample integrity in applications like regenerative medicine and biobanking.
Innovation Solution
A remote monitoring system that includes cryogenic freezers and thawing machines connected to a remote server, allowing for the transmission and receipt of predetermined and actual temperature profiles, enabling real-time data collection and analysis to ensure consistent processing across multiple locations.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If remote monitoring is implemented, then sample integrity is improved, but device complexity increases
Solution Approach 1:
A remote server acts as an intermediary between multiple cryogenic devices and users, centralizing monitoring functions. The server receives temperature data from various freezers and thawing machines, processes it centrally, and provides remote access without requiring complex integration at each device location.
Solution Approach 2:
The remote monitoring system is designed to universally interface with multiple types of cryogenic devices (freezers, thawing machines, transportation devices) through standardized communication protocols. A single system can monitor diverse equipment across different locations, reducing overall system complexity.
2Manufacturing precision
If real-time monitoring is implemented, then processing consistency is improved, but loss of time increases
Solution Approach 1:
Temperature profiles are predetermined and programmed into the cryogenic devices before processing begins. The system pre-establishes freezing and thawing parameters, allowing devices to execute protocols automatically without real-time intervention, thus maintaining consistency while minimizing monitoring delays.
Solution Approach 2:
The system implements feedback mechanisms where actual temperature readings are continuously compared against predetermined profiles. Deviations trigger automated alerts or corrections, ensuring processing consistency is maintained through responsive feedback rather than continuous real-time control.
3Reliability
If multiple devices are monitored centrally, then reliability is improved, but device complexity increases
Solution Approach 1:
The monitoring system is segmented into independent modular components: individual cryogenic devices each with their own sensors and communication modules, a centralized remote server for data aggregation, and client interfaces for user access. This segmentation allows reliable monitoring of multiple devices without creating a monolithic complex system.
Data Source
AI summary
A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server capable of transmitting freezing profile data to one or more freezers, transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.