Removable Housing for Percutaneous Access Device

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Solution Overview

Problem

The blood-brain barrier hinders the delivery of drugs like protein molecules, monoclonal antibodies, and cytotoxic agents to the brain, requiring repeated surgical interventions for septum and filter replacement in percutaneous access apparatus, which is undesirable due to associated risks.

Innovation Solution

A percutaneous fluid access apparatus with a removably attachable housing containing seals and filters, allowing for external replacement without disturbing the skin interface, enabling non-surgical replacement of seals and filters in a healthcare environment, reducing the need for repeated surgeries.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the housing is made permanently fixed to the base portion, then the fluid connection stability is improved, but the ease of replacing seals and filters deteriorates

Engineering Contradiction:

Improvefluid connection stabilityVSAvoidease of replacing seals and filters

Core Design Contradiction:

ReliabilityVSEase of repair

Solution Approach 1:

The device is divided into separate modules: a base portion that remains implanted and a housing containing the seal and filter that can be independently removed and replaced. This segmentation allows the housing to be replaced without disturbing the implanted base portion and skin interface, while maintaining secure fluid connection when attached.

Inventive Principle:

Principle #1Segmentation

2Ease of repair

If the housing is made removably attachable, then the ease of replacing seals and filters is improved, but the risk of inadvertent separation increases

Engineering Contradiction:

Improveease of replacing seals and filtersVSAvoidrisk of inadvertent separation

Core Design Contradiction:

Ease of repairVSReliability

Solution Approach 1:

The housing is pre-configured with attachment features (such as threading, snap-fit mechanisms, or interlocking structures) that enable secure connection to the base portion. This preliminary design ensures that when the housing is attached, it forms a reliable fluid-tight connection that resists inadvertent separation while still allowing intentional removal for maintenance.

Inventive Principle:

Principle #10Preliminary action

3Reliability

If surgical conditions are required for seal and filter replacement, then the aseptic environment is improved, but the surgical risks and patient exposure to complications increase

Engineering Contradiction:

Improveaseptic environmentVSAvoidsurgical risks and complications

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The housing containing the seal and filter is extracted as a separate replaceable component from the implanted base portion. This allows the housing to be replaced in a non-surgical healthcare environment using standard aseptic techniques, eliminating the need for repeated surgical interventions and associated risks while maintaining adequate infection prevention.

Inventive Principle:

Principle #2Taking out (Extraction)

Data Source

PatentUS11638811B2Percutaneous access apparatus

Publication Date: 2023.05.02 RENISHAW PLC

AI summary

A percutaneous fluid access apparatus includes a percutaneous fluid access device. The percutaneous fluid access device has a base portion including a subcutaneous portion and at least one port for connection to one or more fluid conduits within a body of a patient. A housing has at least one fluid channel and at least one seal for sealing the at least one fluid channel, and the housing is removably attachable to the base portion. The at least one fluid channel is in fluid communication with the at least one port when the housing is attached to the base portion.