Removable Stent Structure Using Radial Force for Vasospasm
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Solution Overview
Problem
Current treatments for vasospasm, such as drug therapy and surgical interventions, are inadequate in preventing and treating cerebral vasospasm following subarachnoid hemorrhage, as they are costly, time-consuming, and have limited efficacy, while existing stent structures either provide insufficient radial force or require permanent implantation.
Innovation Solution
A stent structure that is deployed at the site of vasospasm and moved longitudinally to exert a controlled radial force on the vessel wall, inducing denudation of the intima layer, combined with a method of repeated longitudinal movement to treat and prevent vasospasm.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a stent structure is permanently implanted to keep the vessel open, then the vessel remains open, but the device complexity and permanent implantation requirements increase
Solution Approach 1:
The stent structure is designed to be dynamically deployable and removable. It can be deployed in an expanded state to maintain vessel openness and then removed after achieving the therapeutic effect, transforming from a static permanent implant to a dynamic temporary device that adapts to treatment needs.
Solution Approach 2:
The stent structure enables periodic treatment through repeated deployment and removal cycles. The method allows multiple treatment sessions where the stent is deployed, moved longitudinally to induce denudation, and then removed, permitting periodic intervention to treat vasospasm without permanent implantation.
2Reliability
If the stent structure is moved longitudinally to induce denudation, then vasospasm treatment efficacy improves, but the treatment time increases
Solution Approach 1:
The longitudinal movement of the stent structure is performed repeatedly and continuously during the treatment process. Multiple passes of deployment and longitudinal movement are conducted to ensure sufficient denudation of the intima layer, maintaining continuous therapeutic action until the vasospasm is resolved.
Solution Approach 2:
The treatment employs periodic cycles of stent deployment, longitudinal movement, and removal. These repeated cycles create cumulative denudation effect on the vessel wall, with each period contributing to the overall therapeutic outcome, thereby achieving efficacy through time-repeated intervention.
3Reliability
If repeated longitudinal movement is performed to enhance efficacy, then treatment effectiveness improves, but the number of treatment procedures increases
Solution Approach 1:
The stent structure serves multiple functions within a single device: it provides radial force to keep the vessel open, acts as a mechanical stimulus through longitudinal movement to induce denudation, and can be repeatedly deployed and removed for multiple treatment sessions. This multi-functionality consolidates what would otherwise require multiple separate procedures into a single versatile device system.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The stent structure effectively treats vasospasm by denuding the intima layer, reducing vessel constriction and preventing neurological damage, with the potential for repeated treatments to enhance efficacy and minimize side effects.
Implementation Method 1
The stent structure (2) is characterized in that it exerts a radial force on the inner wall of the blood vessel (v)
Implementation Method 2
Friction between the expanded stent structure and the vessel wall has been found to be beneficial in the treatment of vasospasm
Data Source
AI summary
The invention relates to methods and corresponding device for treating a vasospasm with a stent structure, wherein the stent structure has an expanded state in which it lies against the inner wall of a blood vessel and a compressed state in which it is movable through the blood vessel within a catheter, wherein the stent structure is connected, preferably at its proximal end, to a delivery wire, wherein the stent structure is introduced within a catheter to the location in the blood vessel at which a vasospasm is present or predicted, the stent structure is released from the catheter, and the stent structure is moved longitudinally through the blood vessel in the expanded state. Optionally, the stent structure, after released from the catheter, the stent structure is left in position in the expanded state for a limited period of time followed by the longitudinal movement through the blood vessel.