Resonant Amplifier Assembly for Optical Imaging Signal Processing

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Solution Overview

Problem

Heterodyne detected optical imaging apparatus face challenges with high thermal noise, limited signal-to-noise ratio (SNR), slow processing speed, and high complexity and cost of lock-in amplifiers, which hinder their widespread use in microscopy applications.

Innovation Solution

An optical imaging apparatus utilizing a resonant amplifier assembly to isolate, amplify, and rectify the modulated image signal, improving SNR and processing speed while reducing complexity and cost compared to traditional lock-in amplifiers.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a lock-in amplifier is used to extract and amplify the image data signal, then the signal can be filtered from electrical noise and amplified to desired amplitude, but the thermal noise is large which deteriorates the signal-to-noise ratio

Engineering Contradiction:
Improvesignal-to-noise ratioVSAvoidthermal noise
Core Design Contradiction:
Measurement precisionVSObject-generated harmful factors

Solution Approach 1:

The patent extracts only the necessary signal processing functions (bandpass filtering and amplification) from the complex lock-in amplifier and implements them using a simple resonant circuit. This extraction eliminates the source of thermal noise while retaining the essential function of isolating and amplifying the modulated image signal at the specific modulation frequency.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent creates a simplified functional copy of the lock-in amplifier's core capability using a resonant circuit that mimics the bandpass filtering behavior. Instead of using the complex lock-in amplifier architecture, a resonant circuit tuned to the modulation frequency replicates the signal isolation function with minimal thermal noise generation.

Inventive Principle:
Principle #26Copying

2Productivity

If a lock-in amplifier with small time constant is used to improve processing speed, then faster signal processing is achieved, but the minimum time constant is still approximately 20 μs which limits imaging speed

Engineering Contradiction:
Improveimaging speedVSAvoidprocessing time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent replaces the expensive, slow lock-in amplifier with a simple, fast resonant circuit that has no minimum time constant limitation. The resonant circuit provides instantaneous frequency-selective amplification without the integration time requirements of lock-in amplifiers, enabling much faster imaging speeds.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Measurement precision

If a lock-in amplifier is used to isolate and amplify the modulated image signal, then the signal can be extracted from background, but the device is complex and expensive which sets a bottleneck for wide use

Engineering Contradiction:
Improvesignal isolation capabilityVSAvoidamplifier complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts the essential signal isolation function from the complex lock-in amplifier and implements it using a simple resonant circuit consisting of basic electronic components. This extraction maintains the signal isolation capability while eliminating the complexity and high cost of the original lock-in amplifier system.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the operating parameters by tuning the resonant circuit to the specific modulation frequency of the imaging signal. This frequency-selective approach provides effective signal isolation without requiring the complex variable frequency and bandwidth control mechanisms of a lock-in amplifier.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The resonant amplifier assembly enhances the signal-to-noise ratio, accelerates image processing, and decreases the apparatus' size and expense, making it more suitable for microscopy applications such as live cell imaging and pharmaceutical sample analysis.

Implementation Method 1

The resonant amplifier assembly includes a resonant tank circuit configured to isolate the modulated image signal from the background component

Methodology Applied
Scientific EffectResonance: Resonance

Implementation Method 2

The resonant amplifier assembly includes a resonant tank circuit configured to isolate the modulated image signal from the background component, amplify the modulated image signal

Methodology Applied
Scientific EffectResonance: Resonance

Implementation Method 3

The resonant amplifier assembly includes a rectifier assembly configured to rectify the modulated image signal

Methodology Applied
Scientific EffectRectification:

Data Source

PatentUS9222878B2Method and device for optical imaging with a resonant amplifier assembly
Publication Date: 2015.12.29 PURDUE RES FOUND
  • US9222878B2 patent drawing
  • US9222878B2 patent drawing
  • US9222878B2 patent drawing

AI summary

An optical imaging apparatus includes an optical signal source, an optical signal detector apparatus, and a resonant amplifier assembly. The optical signal source is configured (i) to generate an optical signal including a carrier signal and an imaging signal, and (ii) to guide the optical signal to a sample. The optical signal detector apparatus is configured (i) to detect a modified optical signal from the sample, and (ii) to generate an electrical image signal based on the modified optical signal. The electrical image signal includes a background component and a modulated image signal corresponding to an image of the sample. The resonant amplifier assembly is electrically coupled to the optical signal detector apparatus and is configured (i) to isolate the modulated image signal from the background component, (ii) to amplify the modulated image signal, and (iii) to rectify the modulated image signal.