Resorbable Multilayer Film for Bone Defect Sealing

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing bone defect coverings require a second operation to remove the film or membrane after bone augmentation, which is inconvenient and increases the number of procedures needed for recovery.

Innovation Solution

A pre-connected multi-layer film with a resorbable shaping layer for molding onto the bone defect site and a cover layer for sealing, both designed to be completely absorbed by the body, eliminating the need for a second operation by integrating space-forming and sealing properties in a single, easily handled film.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a non-resorbable film or membrane is used for covering bone defect sites, then the film provides stable space-forming and sealing properties, but a second operation is required to remove the film after bone augmentation

Engineering Contradiction:
Improvespace-forming and sealing stabilityVSAvoidnumber of surgical procedures
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The film material's key parameter changed from non-resorbable to resorbable, allowing it to be degraded by hydrolysis in the body. This parameter change enables the film to maintain stability during the bone regeneration period and then automatically dissolve, eliminating the need for a second removal operation.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The film is designed as a temporary, disposable device that serves its function during bone regeneration and then disappears through resorption. This approach replaces permanent implants with temporary structures that fulfill their purpose and then are naturally eliminated by the body.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Ease of operation

If a resorbable multi-layer film is used for covering bone defect sites, then a second removal operation is avoided, but the film must maintain sufficient mechanical strength during bone regeneration

Engineering Contradiction:
Improvenumber of surgical proceduresVSAvoidmechanical strength during resorption
Core Design Contradiction:
Ease of operationVSStrength

Solution Approach 1:

The film uses composite material structure with multiple layers having different properties. The shaping layer provides space-forming strength while the cover layer provides sealing strength. Both layers are made of resorbable materials that maintain sufficient mechanical strength during the bone regeneration period and then progressively degrade.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The film's mechanical properties are designed to be dynamic rather than static. The resorbable materials gradually degrade over time, providing full mechanical support initially and progressively transferring load to the regenerating bone, eventually complete resorption. This dynamic strength profile matches the healing process.

Inventive Principle:
Principle #15Dynamics

3Adaptability or versatility

If the shaping layer and cover layer are made of different resorbable materials, then each layer can be optimized for its specific function, but the manufacturing complexity increases

Engineering Contradiction:
Improvefunctional optimization of layersVSAvoidmanufacturing complexity
Core Design Contradiction:
Adaptability or versatilityVSEase of manufacture

Solution Approach 1:

The film is segmented into functionally distinct layers: a shaping layer for space formation and a cover layer for sealing. Each layer can be made from materials optimized for its specific function, allowing independent optimization of properties such as resorption rate, mechanical strength, and sealing capability.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Despite the functional segmentation, the layers are manufactured as a pre-connected integrated structure. This merging of multiple functional layers into a single pre-assembled unit simplifies the overall manufacturing process and ensures precise alignment during application, offsetting the complexity of using different materials.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The film facilitates bone regeneration by creating a cavity for growth and sealing the defect site without requiring additional surgeries, as it is absorbed during the bone regeneration period, ensuring effective and efficient healing.

Implementation Method 1

the film or membrane as a whole can be completely resorbed in the body, for example by being degraded in the body by hydrolysis

Methodology Applied
Scientific EffectHydrolysis: Hydrolysis

Data Source

PatentEP3102153B1Pre-bonded multilayer film for covering a bone defect site
Publication Date: 2018.11.07 SONNLEITNER DIETMAR
  • EP3102153B1 patent drawingFigure 1~3
  • EP3102153B1 patent drawingFigure 4~7
  • EP3102153B1 patent drawingFigure 8~15

AI summary

The invention relates to a preliminarily bonded multilayer film (1) for covering a bone defect site (2), in particular in the region of a jaw bone, the film (1) comprising at least one shaping molding layer (3) for molding the film (1) onto the bone defect site (2) and at least one cover layer (4, 4a, 4b) for covering the bone defect site (2), the molding layer (3) and the at least one cover layer (4, 4a, 4b) being substantially completely resorbable.