Resorbable Stenosis Cannula for Venous Arterialization
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current coronary venous retroperfusion techniques face challenges such as sudden pressure increases leading to vessel edema and hemorrhage, and the need for invasive procedures and pumps, which can result in high mortality rates and complications like graft clots and atherosclerotic changes.
Innovation Solution
A cannula with a resorbable stenosis or occlusion balloon that gradually increases pressure in the venous system to arterial levels over time, allowing for pre-arterialization of the venous system, eliminating the need for pumps and reducing the risk of vessel rupture and atherosclerotic changes, and enabling percutaneous delivery without open heart surgery.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Stress or pressure
If sudden pressure increase is applied to arterialize the venous system, then retroperfusion can be achieved, but vessel edema and hemorrhage occur
Solution Approach 1:
The patent applies preliminary action by gradually increasing the pressure in the venous system over time before achieving full arterialization. The device progressively adapts the venous vessels to higher pressures through controlled inflation, preventing sudden pressure shocks that would cause edema and hemorrhage.
Solution Approach 2:
The patent implements dynamics by using a controllable inflation mechanism that can adjust pressure levels dynamically. The balloon or occlusion device can be inflated to different degrees and rates, allowing the system to adapt pressure gradually rather than applying a fixed sudden pressure increase.
2Productivity
If invasive procedures and pumps are used for retroperfusion, then blood flow can be controlled, but mortality rates increase and complications occur
Solution Approach 1:
The patent applies self-service by designing a system where the patient's own arterial blood pressure drives the retroperfusion through the venous system. The gradual pressure increase arterializes the venous vessels, allowing them to function as conduits without requiring external pumps or complex mechanical support systems.
Solution Approach 2:
The patent extracts the need for external pumps and complex invasive procedures by utilizing the patient's inherent arterial pressure. The system removes the dependency on mechanical pumps by creating a direct pressure-driven flow from arteries through the arterialized venous system.
3Productivity
If conventional CABG procedure is used, then coronary arteries can be bypassed, but surgical complexity and recovery time increase
Solution Approach 1:
The patent applies inversion by reversing the conventional approach: instead of creating new arterial pathways (CABG), it arterializes existing venous vessels and uses them for retrograde blood flow. This inverted strategy simplifies the procedure by utilizing already-present venous anatomy rather than creating new arterial grafts.
Solution Approach 2:
The patent implements universality by making the venous system multi-functional. The veins serve both their original drainage function and a new function as arterial conduits for retroperfusion, eliminating the need for separate bypass grafts and reducing overall surgical complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The cannula effectively arterializes the venous system, reducing the risk of vessel rupture and atherosclerotic changes, while allowing for minimally invasive, pump-free retroperfusion, thereby improving patient safety and reducing surgical risks and complications.
Implementation Method 1
a cannula with a resorbable stenosis or occlusion balloon that gradually increases pressure in the venous system to arterial levels over time
Implementation Method 2
a regional hypothermia system operably coupled thereto, the regional hypothermia system operable to reduce and/or regulate a temperature of blood flowing therethrough
Data Source
AI summary
Methods and devices for controlling blood perfusion pressure along with regional mild hypothermia. In at least one embodiment of a device for controlling blood perfusion pressure within a vessel of the present disclosure, the device comprises an elongated body having a lumen, a proximal end configured for placement in a first area having a first blood pressure, and a distal end configured for placement in a second area having a second blood pressure, a partial occluder positioned within the lumen of the elongated body between the proximal end and the distal end, the partial occluder configured so not to fully occlude a blood vessel and to equalize the first blood pressure at the first area with the second blood pressure at the second area, and a regional hypothermia system operably coupled thereto, the regional hypothermia system operable to reduce and/or regulate a temperature of a bodily fluid flowing therethrough.