Respiratory Motion Estimation in Emission Imaging

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Solution Overview

Problem

In emission imaging techniques like PET and SPECT, respiratory motion causes image degradation, and existing methods require respiratory monitors to achieve accurate gating, which can be cumbersome and less effective for various radiopharmaceutical distributions and organ movements.

Innovation Solution

An amplitude-based respiratory gating method that estimates respiratory motion by identifying a motion assessment image feature in reconstructed emission imaging data, generating a displacement versus time curve, and binning data into amplitude-based gates to reduce motion blur without the need for respiratory monitors, allowing for more accurate and adaptable motion compensation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If respiratory gating is performed using a respiration monitor belt, then respiratory motion impact is limited, but device complexity increases and ease of operation deteriorates

Engineering Contradiction:
Improverespiratory motion estimation accuracyVSAvoidrespiratory monitor attachment
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The emission imaging device itself serves as the respiratory motion monitoring tool by using its own detected radiation data to generate respiratory gating signals, eliminating the need for external respiration monitor belts or separate monitoring devices

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The emission imaging device performs dual functions: acquiring emission imaging data and simultaneously monitoring respiratory motion through the same detected radiation, making the device multi-functional and eliminating additional equipment

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Measurement precision

If respiratory gating is performed using a respiration monitor, then respiratory motion impact is limited, but ease of operation worsens due to cumbersome monitoring device attachment

Engineering Contradiction:
Improverespiratory motion estimation accuracyVSAvoidmonitoring device attachment
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The emission imaging device uses its own detected radiation data to derive respiratory gating signals, eliminating the need for patients to wear or be attached to external monitoring devices during the imaging procedure

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The respiratory monitoring function is extracted from separate external devices and integrated into the emission imaging data processing itself, removing the need for additional monitoring equipment attachment

Inventive Principle:
Principle #2Taking out (Extraction)

3Manufacturing precision

If conventional respiratory gating is used, then respiratory motion blur is reduced, but adaptability to different radiopharmaceutical distributions and organ movements deteriorates

Engineering Contradiction:
Improveimage qualityVSAvoidadaptability to different radiopharmaceutical distributions
Core Design Contradiction:
Manufacturing precisionVSAdaptability or versatility

Solution Approach 1:

The respiratory gating approach is made dynamic and adaptive by using actual detected emission data from the specific radiopharmaceutical distribution in each patient to derive gating signals, allowing the system to adapt to different organ movements and radiopharmaceutical distributions rather than using fixed gating protocols

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The gating parameters are changed from fixed predetermined values to variable values derived from the actual emission data characteristics, including the specific radiopharmaceutical distribution pattern and resulting organ motion patterns for each imaging case

Inventive Principle:
Principle #35Parameter changes

4Measurement precision

If extended emission imaging data acquisition time is employed to collect enough data, then signal-to-noise ratio is improved, but respiratory motion impact increases

Engineering Contradiction:
Improvesignal-to-noise ratioVSAvoidimage quality
Core Design Contradiction:
Measurement precisionVSManufacturing precision

Solution Approach 1:

The emission imaging data acquisition is organized into periodic respiratory gating cycles, where data are collected and reconstructed for specific phases of the respiratory cycle (such as end-exhalation), allowing extended total acquisition time while maintaining image quality by selectively using data from quiescent respiratory phases

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The extended acquisition time is segmented into multiple respiratory gating cycles, with data sorted into different bins corresponding to different respiratory phases, allowing the system to accumulate sufficient signal while compensating for motion by reconstructing only from appropriate segments

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS11410349B2Methods for data driven respiratory motion estimation
Publication Date: 2022.08.09 KONINKLIJKE PHILIPS NV
  • US11410349B2 patent drawing
  • US11410349B2 patent drawing
  • US11410349B2 patent drawing

AI summary

A respiratory motion estimation method (30) includes reconstructing emission imaging data (22) to generate a reconstructed image (50). The emission imaging data comprises lines of response (LORs) acquired by a positron emission tomography (PET) imaging device or projections acquired by a gamma camera. One or several assessment volumes (66) are defined within the reconstructed images. The emission imaging data are binned into time interval bins based on time stamps of the LORs or projections. A displacement versus time curve (70) is generated by computing, for each time interval bin, a statistical displacement metric of the LORs or projections that both are binned in the time interval bin and intersect the motion assessment volume. The motion assessment volume may be selected to overlap a motion assessment image feature (60) identified in the reconstructed image.