Retinal OCT Layer Mapping via Line-Finding Algorithm

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Solution Overview

Problem

Conventional CNN-based segmentation methods for OCT retinal images are slow, resource-intensive, and require retraining when switching between different OCT imaging systems, making it challenging to accurately and efficiently map out specific retinal layers.

Innovation Solution

A method and apparatus that process OCT image data using a line-finding algorithm to generate mapping data for predetermined anatomical layers of the retina, involving A-scan data processing and cross-correlation with a kernel to accentuate specific bands, allowing for fast and efficient layer mapping without the need for extensive retraining.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If CNN-based segmentation is used to automatically segment OCT retinal images, then layer mapping accuracy is improved, but processing time and computational resources increase significantly

Engineering Contradiction:
Improvelayer mapping accuracyVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent segments the retinal image processing task into distinct stages: initial layer detection using speeded-up robust features (SURF) to identify key anatomical landmarks, followed by separate processing for individual retinal layers. This division allows the computationally intensive CNN to be applied only to critical segmentation points rather than the entire image, reducing overall processing time while maintaining accuracy.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent performs preliminary processing by detecting prominent retinal layers and anatomical landmarks using efficient feature detection algorithms before applying CNN-based segmentation. This preliminary action identifies key structures that guide subsequent CNN processing, reducing the computational burden on the neural network and accelerating overall processing while preserving mapping accuracy.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If CNN is retrained for different OCT imaging systems, then segmentation accuracy for each system is improved, but device complexity and retraining requirements increase

Engineering Contradiction:
Improvesegmentation accuracyVSAvoidretraining requirements
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent develops a universal CNN-based segmentation approach that can process OCT images from multiple imaging systems using a single trained model. The system achieves this by training on diverse datasets from different OCT platforms and incorporating system-specific parameter adjustments that allow the same network architecture to adapt to various imaging characteristics without requiring complete retraining for each system.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent enables adaptation to different OCT imaging systems by modifying network parameters such as learning rate, batch size, and optimization hyperparameters rather than retraining the entire model. This approach allows the same CNN architecture to be efficiently adapted to different systems through parameter tuning rather than full retraining, reducing device complexity while maintaining segmentation accuracy.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If extensive training data is used for CNN segmentation, then segmentation performance is improved, but resource requirements and processing complexity increase

Engineering Contradiction:
Improvesegmentation performanceVSAvoidcomputational resources
Core Design Contradiction:
ReliabilityVSUse of energy by moving object

Solution Approach 1:

The patent extracts and utilizes only the most critical and informative features from training data for CNN segmentation, rather than processing entire images. By identifying and extracting key anatomical landmarks and layer boundaries as primary training targets, the system achieves high segmentation performance with reduced computational resources compared to training on complete retinal images.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent applies partial action by focusing CNN training on specific critical regions and layers of the retina that are most important for accurate segmentation, rather than uniformly processing all retinal structures. This selective approach maintains high segmentation performance for clinically relevant layers while reducing the overall computational burden of training and inference.

Inventive Principle:
Principle #16Partial or excessive action

Data Source

PatentUS11625826B2Retinal OCT data processing
Publication Date: 2023.04.11 OPTOS PLC
  • US11625826B2 patent drawing
  • US11625826B2 patent drawing
  • US11625826B2 patent drawing

AI summary

A method of method of processing optical coherence tomography, OCT, image data representing an OCT image of a retina of an eye, to generate mapping data which maps out a predetermined band of a plurality of distinct bands which extend across the OCT image and correspond to respective anatomical layers of the retina. The method comprises: receiving the OCT image data; processing A-scan data of the received OCT image data to generate data indicative of sequences of A-scan elements corresponding to the predetermined band of the plurality of distinct bands and having respective A-scan element values that vary in accordance with a predetermined pattern; and generating the mapping data by applying a line-finding algorithm to determine a line passing through the sequences of A-scan elements indicated by the generated data.