Retinal Phase Map Projection for Rapid Choroidal Topography Assessment
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Solution Overview
Problem
Current methods for assessing the effectiveness of ophthalmic lens designs in preventing myopia progression are limited by the need for long-term clinical studies, and there is a lack of tools to determine short-term changes in choroidal topography due to lens designs.
Innovation Solution
An apparatus and method that project at least two individual phase maps simultaneously to different retinal eccentricities, allowing for the determination of choroidal topography over a region on the retina, including foveal and peripheral regions, to assess the effect of ophthalmic lens designs.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If long-term clinical studies are used to assess the effectiveness of ophthalmic lens designs, then the reliability of the assessment is improved, but the time required for assessment increases significantly
Solution Approach 1:
The patent applies preliminary action by measuring choroidal topography changes over a short period (e.g., 30 minutes to 24 hours) after lens application as an early indicator of long-term myopia progression effects. This preliminary measurement allows assessment of lens effectiveness before long-term clinical studies are completed, significantly reducing the time required while maintaining predictive value for long-term outcomes
2Measurement precision
If only central retinal region is measured, then the measurement precision is improved, but the area of measurement is reduced
Solution Approach 1:
The patent applies segmentation by measuring choroidal topography at multiple discrete retinal locations including both the central region (within 15 degrees of the visual axis) and peripheral regions (more than 15 degrees from the visual axis). This segmented approach allows simultaneous assessment of different retinal areas while maintaining measurement precision at each location, providing comprehensive information about lens effects across the entire retina
Solution Approach 2:
The patent extends the measurement from a single central point to multiple dimensions by incorporating both central and peripheral retinal regions. This dimensional expansion allows assessment of how ophthalmic lenses affect different parts of the retina, providing a more complete picture of lens performance while maintaining precision through systematic measurement protocols
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables the rapid determination of choroidal topography changes in response to ophthalmic lens designs, facilitating the optimization of lens designs before clinical studies and providing insights into long-term effects.
Implementation Method 1
an interferometer configured to produce optical interference using light reflected from the user's/subject's eye
Data Source
AI summary
An apparatus and a method for determining a choroidal topography over a region on a retina of an eye of a person are disclosed. The apparatus is also used to determine an effect of an ophthalmic lens design on the choroidal topography. The apparatus includes two individual displays, two optical transfer elements, a measuring device, and an optical filter. The displays provide a retinal stimulus and the optical transfer elements projects the retinal stimulus or a phase map to a region on a retina. The phase map contains a modified retinal stimulus. The measuring device images a choroidal topography over the region on the retina by capturing reflected light. The optical filter separates the reflected light from the projected phase map. Further, the second optical transfer element simultaneously projects the individual phase maps at a different retinal eccentricity to a peripheral region and a foveal region of the retina.