Retinol Stabilization Using Ethylenediaminedisuccinic Acid Salt
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Solution Overview
Problem
Cosmetic compositions containing retinol for anti-aging skin care are unstable due to rapid degradation from light, oxygen, metal ions, oxidizing agents, and temperature, leading to unpleasant odors and limited use, with existing stabilization methods using BHT and EDTA being toxic and environmentally unfriendly, and ineffective in oil-in-water emulsions.
Innovation Solution
A cosmetic composition comprising retinol, ethylenediaminedisuccinic acid salt, ascorbic acid or its analog, and tocopherol or its derivative, which stabilizes retinol effectively, reducing degradation and maintaining a pleasant odor and color, while minimizing the use of controversial ingredients.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If retinol is formulated in cosmetic compositions, then anti-aging efficacy is improved, but stability deteriorates due to rapid degradation from light, oxygen, metal ions, oxidizing agents, and temperature
Solution Approach 1:
The patent introduces ethylenediaminedisuccinic acid salt as a stabilizing agent that acts as an intermediary to protect retinol from degradation. This compound chelates metal ions and prevents oxidative degradation, thereby maintaining retinol stability without compromising its anti-aging efficacy. The stabilizer mediates between the retinol and harmful environmental factors.
Solution Approach 2:
The patent modifies the chemical environment by introducing ethylenediaminedisuccinic acid salt, which changes the pH and chelating properties of the formulation. This parameter change creates a more favorable environment for retinol stability, preventing degradation from light, oxygen, and metal ions while maintaining the active ingredient's efficacy.
2Stability of the object's composition
If BHT and EDTA are used to stabilize retinol, then retinol stability is improved, but toxicity and environmental harm worsen
Solution Approach 1:
The patent replaces long-term harmful stabilizers (BHT and EDTA) with a biodegradable, environmentally friendly alternative (ethylenediaminedisuccinic acid salt). This new stabilizer provides the necessary protection temporarily during product shelf life but degrades harmlessly afterward, eliminating cumulative toxicity and environmental persistence issues.
Solution Approach 2:
The patent changes the chemical composition parameters by substituting controversial stabilizers with ethylenediaminedisuccinic acid salt, which has different safety and environmental profiles. This parameter change maintains the required stabilizing function while improving the safety and environmental compatibility of the formulation.
3Stability of the object's composition
If retinol is stabilized with conventional methods, then degradation is reduced, but unpleasant odor develops limiting use
Solution Approach 1:
The ethylenediaminedisuccinic acid salt acts as an intermediary that prevents the chemical reactions leading to odor generation. By chelating metal ions and preventing oxidative degradation, it stops the formation of degraded retinol compounds that produce unpleasant odors, thereby maintaining both stability and sensory acceptability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition significantly reduces retinol degradation, maintaining stability and pleasant organoleptic properties, making it suitable for long-term storage and repeated use without the use of toxic or environmentally harmful stabilizers.
Implementation Method 1
the degradation of retinol is rapid, due to the effect of light, oxygen, metal ions, oxidizing agents, water or, in particular, due to an increase in temperature
Data Source
AI summary
The present invention relates to a composition, especially a cosmetic composition, in particular for making up and/or caring for keratin materials, comprising at least retinol, an ethylenediaminedisuccinic acid salt, at least one compound chosen from ascorbic acid or an analog thereof, and tocopherol or a derivative thereof.