Non-Invasive RF Glucose Monitoring via Machine Learning Waveform Matching

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Solution Overview

Problem

Current methods for monitoring real-time glucose levels in patients, especially during surgery, are inaccurate due to the invasive nature of blood sampling and the need for continuous testing, which can lead to gaps in measurement and complications such as delayed healing, wound infections, and neurological issues.

Innovation Solution

A radio frequency health monitoring system that uses wearable devices to transmit and receive RF signals within a specific range, converting them into digital format for processing, and employing machine learning to match glucose waveforms with standard patterns, while adjusting for motion, temperature, and noise to provide accurate and continuous glucose monitoring.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If invasive blood sampling is used for glucose monitoring, then measurement accuracy is improved, but patient safety deteriorates due to surgical complications

Engineering Contradiction:
Improveglucose measurement accuracyVSAvoidsurgical complications
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent replaces the mechanical invasive blood sampling system with a non-invasive optical detection system. The system uses light absorption spectroscopy to measure glucose levels through blood flow in the tissue, eliminating needles and invasive procedures while maintaining continuous monitoring capability. This substitution resolves the contradiction by removing the harmful invasive element while preserving measurement functionality.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces an optical intermediary (light) to mediate between the glucose molecules and the detector. Instead of directly extracting and analyzing blood samples, the system uses light absorption characteristics of glucose-containing blood flow to indirectly measure glucose levels. This intermediary approach enables non-invasive measurement, resolving the contradiction between accuracy and patient safety.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Speed

If continuous blood sampling is performed, then real-time glucose monitoring is improved, but measurement reliability deteriorates due to gaps and inaccuracies

Engineering Contradiction:
Improvemonitoring speedVSAvoidmeasurement reliability
Core Design Contradiction:
SpeedVSReliability

Solution Approach 1:

The patent implements continuous optical monitoring of glucose levels by continuously detecting light absorption changes in blood flow. Unlike discrete blood sampling, the system maintains uninterrupted measurement by continuously analyzing the optical properties of flowing blood through the tissue, ensuring both real-time monitoring and consistent data reliability without gaps.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The system performs preliminary calibration and baseline establishment before surgical procedures begin, creating reference profiles for each patient. This preliminary action enables the system to accurately interpret real-time optical signals during surgery, improving both the speed and reliability of glucose monitoring by having pre-established reference data for comparison.

Inventive Principle:
Principle #10Preliminary action

3Object-affected harmful factors

If non-invasive optical detection is used, then patient safety is improved, but measurement precision deteriorates due to signal interference

Engineering Contradiction:
Improvesurgical complicationsVSAvoidglucose measurement accuracy
Core Design Contradiction:
Object-affected harmful factorsVSMeasurement precision

Solution Approach 1:

The patent applies local quality by selecting specific wavelengths of light that are optimally absorbed by glucose molecules while minimizing interference from other tissue components. The system uses multiple discrete wavelengths, each optimized for detecting specific glucose-related optical signatures, thereby achieving precise measurements through non-invasive means by tailoring the optical properties to the specific measurement goal.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The system implements feedback mechanisms by continuously comparing real-time optical signals against reference profiles and using algorithms to compensate for variations in tissue properties, blood flow rates, and environmental factors. This feedback loop maintains measurement precision despite the non-invasive approach by dynamically adjusting for interfering signals and validating readings against established baselines.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables real-time, accurate monitoring of glucose levels, reducing the risk of surgical complications by providing continuous and reliable data, thus improving patient safety and surgical outcomes.

Implementation Method 1

A radio frequency health monitoring system that uses wearable devices to transmit and receive RF signals within a specific range

Methodology Applied
Scientific EffectRadio frequency signal transmission and reception: Electromagnetic Induction

Implementation Method 2

converting them into digital format for processing

Methodology Applied
Scientific EffectSignal conversion from RF to digital: Electromagnetic Induction

Data Source

PatentUS12193810B2System and method for performing surgery with real-time health parameter monitoring
Publication Date: 2025.01.14 KNOW LABS INC
  • US12193810B2 patent drawing
  • US12193810B2 patent drawing
  • US12193810B2 patent drawing

AI summary

Methods of using a system for real-time monitoring of blood glucose levels and other analyte levels to reduce the risk of surgical complications. The system includes an apparatus for generating radio frequency scanning data which includes a transmitter for transmitting radio waves below the skin surface of a person and a two-dimensional array of receive antennas for receiving the radio waves, including a portion of the transmitted radio waves that interact with a blood vessel of the person. The wave signal is compared to known standard waveforms, and similar waveforms are input into a machine learning algorithm to determine one or more health parameters of the person. The apparatus is used to collect glucose waveform data. A second apparatus is used to collect waveform data on another analyte. The glucose waveform is analyzed to determine the patient's blood glucose level. The system reports risks associated with the patient's glucose level.