RF Power Distribution for Rapid Electron Beam Steering

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Solution Overview

Problem

Current radiation therapies are hindered by patient, target, and organ motion during treatment delivery, leading to prolonged treatment times and reduced precision, which can result in increased normal tissue toxicity and decreased tumor control efficacy.

Innovation Solution

A system utilizing a compact high-gradient, very high energy electron linear accelerator with electromagnetic or radiofrequency deflection steering, capable of delivering an entire radiation dose in less than 10 seconds, thereby freezing physiologic motion and enhancing dose conformity and tumor control efficacy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional radiation therapy delivery methods are used, then dose distribution accuracy is improved, but treatment time is prolonged (15-90 minutes per fraction)

Engineering Contradiction:
Improvedose distribution accuracyVSAvoidtreatment time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The treatment delivery is segmented into multiple independent beam directions that can be executed in rapid succession. Instead of delivering radiation from one direction at a time using mechanical rotation, the system uses multiple fixed accelerator structures arranged around the patient, allowing parallel preparation and sequential delivery without mechanical movement delays.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The mechanical gantry rotation system is replaced with an electromagnetic/phased-array system. Multiple fixed accelerator structures use electronic phase control to direct beams from different angles, eliminating the need for slow mechanical rotation while maintaining the ability to deliver radiation from multiple directions for accurate dose distribution.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Manufacturing precision

If motion management strategies are implemented, then treatment precision is improved, but treatment complexity and time are increased

Engineering Contradiction:
Improvetreatment precisionVSAvoidmotion management complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The treatment is delivered so rapidly that physiologic motion is effectively frozen during the delivery process. By completing the entire treatment in seconds rather than minutes, the system eliminates the need for complex motion management strategies such as respiratory gating or real-time tracking, as the treatment is completed before significant motion can occur.

Inventive Principle:
Principle #10Preliminary action

3Productivity

If multiple high-power RF sources are used to deliver rapid treatment, then treatment speed is improved, but system cost and complexity increase

Engineering Contradiction:
Improvetreatment speedVSAvoidsystem complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

Multiple lower-power RF sources are combined through a phased-array system to achieve the equivalent effect of a single high-power source. The RF power from multiple sources is coherently combined and directed to different accelerator structures, allowing rapid sequential beam delivery without requiring each individual source to be extremely high-power, thereby reducing overall system cost and complexity.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for rapid, precise radiation delivery with improved dose conformity and reduced toxicity, potentially increasing tumor control efficacy and reducing treatment time, while maintaining a compact and cost-effective system comparable to conventional photon therapy.

Implementation Method 1

an RF phase array coupling the RF power sources with the accelerating structures

Methodology Applied
Scientific EffectRF phase array coupling: Waveguide

Implementation Method 2

control a phase and an amplitude of the RF phase array such that a total RF energy from the RF power sources is directed to a select accelerating structure of the array through source phasing

Methodology Applied
Scientific EffectSource phasing: Phase Modulation

Implementation Method 3

electromagnetic or radiofrequency deflection steering

Methodology Applied
Scientific EffectElectromagnetic deflection: Lorentz Force

Implementation Method 4

electromagnetic or radiofrequency deflection steering

Methodology Applied
Scientific EffectRadiofrequency deflection: Electromagnetic Propulsion

Implementation Method 5

Each of the power sources may include a pulse compressor to boost a peak power output

Methodology Applied
Scientific EffectPulse compression: Compression

Data Source

PatentUS10485991B2Methods and systems for RF power generation and distribution to facilitate rapid radiation therapies
Publication Date: 2019.11.26 THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV
  • US10485991B2 patent drawing
  • US10485991B2 patent drawing
  • US10485991B2 patent drawing

AI summary

Methods and system for facilitating rapid radiation treatments are provided herein and relate in particular to radiation generation and delivery, power production and distribution, and electron source design. The methods and systems described herein are particularly advantageous when used with a compact high-gradient, very high energy electron (VHEE) accelerator and delivery system (and related processes) capable of treating patients from multiple beam directions with great speed, using all-electromagnetic or radiofrequency deflection steering is provided, that can deliver an entire dose or fraction of high-dose radiation therapy sufficiently fast to freeze physiologic motion, yet with a better degree of dose conformity or sculpting than conventional photon therapy.