RF Pulse Design for MRI Off-Resonance Mitigation

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Magnetic resonance imaging (MRI) systems face image degradation due to off-resonance effects caused by magnetic field inhomogeneities, which current methods partially address through shimming and pulse timing optimizations but not fully, leading to artifacts like dark stripe artifacts and incomplete excitation in spectrally sensitive sequences.

Innovation Solution

Designing RF pulses with specific spatial phase distributions that match the phase evolution induced by magnetic field inhomogeneities, incorporating B0 shim values into RF pulse design to optimize B1 field distribution, allowing for joint optimization of RF channels, gradients, and non-linear field variations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If shimming is used to adjust magnetic field uniformity, then image quality improves, but device complexity and cost increase due to higher-order shimming requirements

Engineering Contradiction:
Improvemagnetic field uniformityVSAvoidshimming system complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent replaces the mechanical shimming system with a computational approach. Instead of relying on physical shim coils to correct field inhomogeneities, the system uses computer-based pulse design algorithms that calculate and apply phase corrections to RF pulses, substituting hardware-based field adjustment with software-based signal processing.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the parameters of RF pulses (amplitude, phase, duration) through computational optimization to compensate for magnetic field inhomogeneities. By modifying pulse parameters rather than physical field parameters, the system achieves field uniformity effects without requiring complex shimming hardware.

Inventive Principle:
Principle #35Parameter changes

2Manufacturing precision

If RF pulse duration is extended to improve excitation coverage, then excitation completeness improves, but temporal resolution and productivity deteriorate

Engineering Contradiction:
Improveexcitation completenessVSAvoidimaging speed
Core Design Contradiction:
Manufacturing precisionVSProductivity

Solution Approach 1:

The patent employs dynamic RF pulse sequences where pulse parameters are continuously adjusted during the sequence to track and compensate for off-resonance effects. This dynamic adaptation allows for shorter pulse durations while maintaining excitation completeness, as the system actively corrects phase errors rather than relying on extended pulse lengths.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent uses periodic refocusing pulses with optimized timing and phase relationships to maintain excitation completeness over shorter durations. By strategically timing these periodic pulses, the system achieves complete excitation coverage without requiring continuously extended pulse sequences.

Inventive Principle:
Principle #19Periodic action

3Device complexity

If standard RF pulses are used without off-resonance compensation, then device complexity remains low, but image quality deteriorates due to artifacts

Engineering Contradiction:
Improvepulse design complexityVSAvoidimage quality
Core Design Contradiction:
Device complexityVSManufacturing precision

Solution Approach 1:

The patent replaces hardware-based field correction systems with computational pulse design. Instead of using complex shim coils or field-adjustment hardware, the system uses computer-calculated RF pulse parameters to compensate for off-resonance effects, substituting mechanical field adjustment with digital signal processing.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent implements self-correcting RF pulses that automatically compensate for off-resonance effects through embedded phase modulation. The pulses are designed to inherently counteract their own susceptibility-induced phase errors, making the system self-correcting without requiring external hardware intervention.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach effectively mitigates off-resonance effects by tracking the temporal evolution of magnetic field inhomogeneities, improving image quality in MRI by reducing artifacts and ensuring complete excitation in spectrally sensitive sequences.

Implementation Method 1

radio-frequency (RF) pulses are designed for use in exciting nuclear spins in order to obtain magnetic resonance image data

Methodology Applied
Scientific EffectNuclear magnetic resonance:

Implementation Method 2

spatial variations of the B0 field, or equivalently, the resonance frequency, may lead to unwanted local signal behavior

Methodology Applied
Scientific EffectLarmor precession:

Data Source

PatentUS8866478B2Method and processor and magnetic resonance apparatus for designing RF pulses to mitigate off-resonance effects
Publication Date: 2014.10.21 THE GENERAL HOSPITAL CORP
  • US8866478B2 patent drawing
  • US8866478B2 patent drawing
  • US8866478B2 patent drawing

AI summary

In a magnetic resonance apparatus and operating method therefor, and in a processor that is programmed to design RF pulses for operating such a magnetic resonance apparatus, the RF pulses are designed to mitigate off-resonance effects caused by inhomogeneity of the basic (B0) magnetic field in the magnetic resonance apparatus. The RF pulses of a parallel transmit array are designed with different spatial phase distributions, that deviate from a constant phase from pulse-to-pulse, with the absolute value of the difference between respective spatial phase distributions of any two successively radiated RF pulses corresponding to the off-resonance that is caused by B0-inhomogeneity during the time between the radiation of the successive pulses. Additionally, or separately, currents supplied to the shim coils can be taken into account in the design of the RF pulses as an additional degree of freedom, with the shimming of the basic magnetic field produced by the shim currents deviating from shim currents designed to ideally produce a homogenous B0 field.