RF Passive Modulation for Medication Adherence Monitoring

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Solution Overview

Problem

Nonadherence to medication regimens is a significant issue, with up to 50% of medications not being taken as prescribed, leading to negative health effects and distorted data in clinical research, and existing smart medication containers face challenges due to fragility, cost, and reliability concerns.

Innovation Solution

A radio frequency passive modulation system that uses a remote with a membrane containing a radio frequency passive modulator, piezoelectric element, and RF receiver to detect and record medication use without requiring a power source or smart functionality in the medication container, utilizing ambient RF signals and a base processor to register and communicate dispensing events.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If smart functionality and power sources are added to medication containers to detect and report use, then measurement capability is improved, but device complexity, cost, and weight increase

Engineering Contradiction:
Improvemedication use detection capabilityVSAvoidcontainer component complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent introduces a separate remote device as an intermediary that performs the complex detection, processing, and communication functions. The medication container itself remains simple, while the remote device equipped with processor, memory, and communication capabilities handles the smart functionality. This mediator approach allows measurement capability improvement without increasing container complexity.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system is divided into two distinct segments: a simple medication container and a sophisticated remote device. The container only needs basic structure, while the remote device contains all the complex components including processor, memory, communication interface, and power source. This segmentation resolves the contradiction by placing complexity in the remote segment rather than the container segment.

Inventive Principle:
Principle #1Segmentation

2Measurement precision

If sensors, processors, and communicators are integrated into medication containers to provide smart functionality, then measurement precision is improved, but weight and bulk increase

Engineering Contradiction:
Improvemedication use detection accuracyVSAvoidcontainer weight
Core Design Contradiction:
Measurement precisionVSWeight of moving object

Solution Approach 1:

The remote device serves as an intermediary that bears the weight of all electronic components including sensors, processors, and communicators. The medication container remains lightweight, while the separate remote device contains the heavy electronic subsystems. This resolves the weight contradiction by transferring mass to the remote device.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

Instead of embedding complex electronics in the container, the system uses a remote device that copies or replicates the smart functionality externally. The remote device acts as a digital twin or extension of the container's functionality, providing measurement and communication capabilities without adding physical mass to the container itself.

Inventive Principle:
Principle #26Copying

3Loss of information

If wireless communication components are added to medication containers to transmit data, then data communication capability is improved, but power consumption and device complexity increase

Engineering Contradiction:
Improvedata transmission capabilityVSAvoidpower consumption
Core Design Contradiction:
Loss of informationVSUse of energy by moving object

Solution Approach 1:

The remote device acts as an intermediary communication hub that handles all wireless data transmission. The medication container requires no communication components, while the remote device contains the wireless interface and power source. This resolves the power consumption contradiction by concentrating energy requirements in the remote device that can be charged and managed separately.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Use of energy by moving object

If physical connection requirements are imposed for data download, then power consumption is reduced, but ease of operation deteriorates

Engineering Contradiction:
Improvepower consumptionVSAvoiddata access convenience
Core Design Contradiction:
Use of energy by moving objectVSEase of operation

Solution Approach 1:

The patent replaces the mechanical connection system (physical cables and ports) with a wireless communication system. The remote device uses wireless interfaces to transmit data without requiring physical connections. This substitution improves ease of operation by eliminating the need for plugging and unplugging cables, while the power consumption is managed by the remote device's battery rather than the container.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Provides a reliable, cost-effective, and user-transparent method to monitor medication adherence, reducing the burden on patients and improving data accuracy in clinical settings by detecting medication use without the need for additional power or complex components in the container.

Implementation Method 1

a piezoelectric element engaged with the flexible region and in communication with the radio frequency passive modulator, the RF receiver, the LO generator, and the IF emitter such that when the flexible region is deformed the piezoelectric element deforms therewith and energizes the radio frequency passive modulator, the RF receiver, the LO generator, and the IF emitter

Methodology Applied
Scientific EffectPiezoelectric effect: Piezoelectric Effect

Implementation Method 2

a radio frequency passive modulator disposed in the membrane and adapted to apply a frequency modification to an RF signal by frequency mixing an LO signal therewith so as to produce an IF signal characteristic of the radio frequency passive modulator, the RF signal, and the LO signal

Methodology Applied
Scientific EffectFrequency mixing: Heterodyne

Data Source

PatentUS10565849B2Determining use of medication through radio frequency passive modulation
Publication Date: 2020.02.18 SANTEN HOLDINGS U S INC
  • US10565849B2 patent drawing
  • US10565849B2 patent drawing
  • US10565849B2 patent drawing

AI summary

An RF signal is provided by a base such as a smart phone. A remote is engaged with a medication container. The remote includes an RFPM, RF signal receiver, LO signal generator, and IF signal emitter. An energizer on the remote provides power only as medication is dispensed. While energized, the RFPM modulates the RF signal with an LO signal to produce an IF signal. The existence of the IF signal (characteristic of the RFPM, RF signal, and LO signal) thus indicates medication has been dispensed. The IF signal is detected in the base, and registered (recorded, displayed, communicated, etc.) as an indication that medication has been dispensed. The remote may be configured as a label applied to or a sleeve engaged with an otherwise “non-smart” container. This provides authenticated data regarding medication adherence, transparent to the user and requiring no additional user actions to register the data.