Rhamnolipid Cation Complexes for Controlled Release Biopesticides

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Solution Overview

Problem

Rhamnolipids, despite their antimicrobial and surfactant properties, require high concentrations for effective use as biopesticides, leading to ecological stress and increased costs due to frequent applications, and are not selective enough to target specific pests effectively.

Innovation Solution

Development of rhamnolipid-based biopesticide compositions that include rhamnolipid complexes with cations such as calcium, magnesium, and sodium, which control the release rate of rhamnolipids, allowing for a slower or faster release to provide extended protection and reduce the need for frequent applications.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If high concentrations of rhamnolipids are used to achieve effective pest control, then antimicrobial activity is improved, but ecological stress and cost increase

Engineering Contradiction:
Improveantimicrobial activityVSAvoidecological stress
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the concentration parameter of rhamnolipids from high to low by utilizing synergistic combinations with other bioactive compounds. This allows achieving effective pest control at lower rhamnolipid concentrations, thereby reducing ecological stress while maintaining reliability of antimicrobial activity.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates composite biopesticide formulations combining rhamnolipids with other bioactive compounds such as plant extracts, essential oils, or microbial metabolites. This composite approach enhances the overall antimicrobial efficacy, allowing reduced rhamnolipid dosage while maintaining or improving pest control effectiveness.

Inventive Principle:
Principle #40Composite materials

2Reliability

If high concentrations of rhamnolipids are used to achieve effective pest control, then antimicrobial activity is improved, but application frequency and cost increase

Engineering Contradiction:
Improveantimicrobial activityVSAvoidapplication frequency
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent modifies the concentration parameter to enable longer-lasting effects at lower doses. By combining rhamnolipids with compounds that have complementary modes of action and persistence characteristics, the formulation maintains effective pest control over extended periods, reducing application frequency while preserving antimicrobial reliability.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent designs formulations that provide continuous pest protection through sustained release mechanisms or compounds with prolonged activity. The synergistic combination ensures that as one component degrades, others maintain protective levels, creating continuous useful action that reduces the need for frequent reapplication.

Inventive Principle:
Principle #20Continuity of useful action

3Reliability

If high concentrations of rhamnolipids are used to achieve effective pest control, then broad-spectrum activity is improved, but selectivity decreases

Engineering Contradiction:
Improvebroad-spectrum activityVSAvoidselectivity
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent applies the local quality principle by combining rhamnolipids with target-specific bioactive compounds. While rhamnolipids provide broad-spectrum baseline protection, the added compounds offer selective targeting of specific pest species or life stages. This creates a layered protection strategy where general and specific activities work together, maintaining selectivity while preserving broad-spectrum reliability.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent uses partial action by employing sub-lethal concentrations of rhamnolipids in combination with other compounds. Rather than relying on high concentrations for complete broad-spectrum coverage, the formulation uses moderate rhamnolipid levels supplemented by compounds that provide the necessary spectral coverage, thereby improving selectivity while maintaining overall effectiveness.

Inventive Principle:
Principle #16Partial or excessive action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The controlled release of rhamnolipids effectively treats pathogens while minimizing ecological impact and reducing application frequency, providing both immediate and prolonged protection against pests without harming seeds or plants.

Implementation Method 1

rhamnolipid complexes with cations such as calcium, magnesium, and sodium, which control the release rate of rhamnolipids

Methodology Applied
Scientific EffectComplexation:

Implementation Method 2

Based on the surfactant properties, rhamnolipid solutions first act to detach and remove particles (including living organisms, spores, 'eggs' of pests) from surfaces of plants

Methodology Applied
Scientific EffectSurfactant: Surfactant

Implementation Method 3

Rhamnolipids have been found to have antimicrobial properties. They can inhibit microbial growth and damage or kill microbial cells at concentrations above certain critical levels

Methodology Applied
Scientific EffectAntimicrobial activity:

Implementation Method 4

a biopesticide composition comprising a solvent and a plurality of rhamnolipid complexes

Methodology Applied
Scientific EffectEvaporation: Evaporation

Data Source

PatentUS9992998B2Rhamnolipid based biopesticides
Publication Date: 2018.06.12 THE UNIVERSITY OF AKRON
  • US9992998B2 patent drawing
  • US9992998B2 patent drawing
  • US9992998B2 patent drawing

AI summary

A biopesticide composition includes a solvent and a plurality of rhamnolipid complexes, each rhamnolipid complex including a rhamnolipid complexed with a cation. The biopesticide composition may include a slower-releasing rhamnolipid-based material and a faster-releasing rhamnolipid-based material. The biopesticide composition may be in the form of a coating or a pellet.