Two-Chamber Combined Container-Syringe With Rib-Stabilized Mixing

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Solution Overview

Problem

Conventional two-chamber type combined container-syringes face issues with sealability and stability, leading to leakage and inefficient mixing of medicinal fluids and agents, as well as shaking of the plunger rod, which affects the accuracy and stability of drug preparation.

Innovation Solution

A two-chamber type combined container-syringe design with specific stopper configurations, support ribs on the plunger rod, and optimized chamber ratios, along with enhanced sealing mechanisms to improve stability and prevent leakage.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If the plunger is pushed rapidly to mix the medicinal fluid and agent quickly, then the mixing speed is improved, but the medicinal fluid leaks through gaps and grooves causing contamination and inaccurate preparation

Engineering Contradiction:
Improvemixing speedVSAvoidsealability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent changes the physical parameters of the plunger rod by adding support ribs that protrude into the medicinal fluid. These ribs create additional flow resistance and alter the fluid dynamics, preventing rapid leakage through gaps while still allowing controlled mixing when the plunger is pushed.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The support ribs act as intermediary elements between the plunger rod and the medicinal fluid. They mediate the interaction by creating a barrier that prevents direct contact between the plunger and the fluid gaps, thereby preventing leakage while maintaining the mixing function.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If the plunger rod is made smooth to reduce friction, then the ease of operation is improved, but the plunger rod shakes during use affecting mixing accuracy

Engineering Contradiction:
ImprovefrictionVSAvoidplunger rod stability
Core Design Contradiction:
Ease of operationVSStability of the object's composition

Solution Approach 1:

The plunger rod is segmented by adding multiple support ribs at different positions along its length. These ribs divide the continuous surface into sections, providing structural reinforcement that prevents shaking while maintaining a relatively smooth overall surface that reduces friction during operation.

Inventive Principle:
Principle #1Segmentation

3Device complexity

If the chamber volumes are equal to simplify the structure, then the device complexity is reduced, but the mixing efficiency and accuracy are compromised

Engineering Contradiction:
Improvechamber configurationVSAvoiddrug preparation accuracy
Core Design Contradiction:
Device complexityVSManufacturing precision

Solution Approach 1:

The patent changes the volumetric parameter by specifying that the first chamber volume should be 1.5 to 3 times larger than the second chamber volume. This parameter optimization ensures adequate space for the medicinal agent in the larger first chamber while maintaining a manageable overall structure, thereby achieving both simplicity and precision in drug preparation.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The design ensures effective mixing of medicinal agents and fluids, enhances sealability, reduces plunger rod shaking, and maintains the accuracy of drug preparation by preventing leakage and improving user convenience.

Implementation Method 1

a plunger rod that is connected to the third stopper and has a plurality of support ribs provided to come in contact with an inner surface of the finger grip

Methodology Applied
Scientific EffectFriction: Friction

Implementation Method 2

a groove portion of which a portion protrudes outward is formed in an inner surface of a middle portion of the cylinder. Due to the groove portion, the medicinal fluid accommodated in the second chamber may bypass into the groove portion along an edge of the middle stopper and move to the first chamber

Methodology Applied
Scientific EffectFluid flow through groove: Groove

Implementation Method 3

three stoppers (also referred to as 'plugs' or 'gaskets') are inserted into the cylinder of the syringe

Methodology Applied
Scientific EffectSealing contact: Friction

Data Source

PatentUS12447110B2Two-chamber type combined container-syringe
Publication Date: 2025.10.21 DAEWOONG PHARM CO LTD
  • US12447110B2 patent drawing
  • US12447110B2 patent drawing
  • US12447110B2 patent drawing

AI summary

The present invention provides a two-chamber type combined container-syringe including: a cylinder having a first end portion, a second end portion in an opposite direction of the first end portion, and a bypass portion disposed between the first end portion and the second end portion; a finger grip mounted on the second end portion of the cylinder; a first stopper, a second stopper, and a third stopper that are sequentially disposed from the first end portion toward the second end portion in a space of the cylinder; and a plunger rod that is connected to the third stopper and has a plurality of support ribs provided to come in contact with an inner surface of the finger grip, wherein a space between the first stopper and the second stopper forms a front chamber, a space between the second stopper and the third stopper forms a rear chamber, a first ingredient and a second ingredient are accommodated in the front chamber and the rear chamber, respectively, a length ratio of the front chamber and the rear chamber is in a range of 1.6:1 to 3:1 when the plunger rod is at an initial position which is a state before the front chamber and the rear chamber communicate with each other through the bypass portion, and at the initial position, one or more support ribs are disposed in at least one of the finger grip and a region in the cylinder that is adjacent to the finger grip.