RNA-Protein Interaction Prediction via Multi-Model Vectorization

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Solution Overview

Problem

Current methods for studying RNA-protein interactions are expensive and time-consuming, limiting the ability to efficiently analyze and predict these interactions.

Innovation Solution

A method and apparatus for predicting RNA-protein interactions by acquiring RNA-protein pairs, extracting sequence features, vectorizing RNA and protein sequences, and using multiple interaction prediction models to determine interaction probabilities.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If experimental methods are used to study RNA-protein interactions, then interaction data can be obtained, but the process is expensive and time-consuming

Engineering Contradiction:
Improveinteraction data accuracyVSAvoidanalysis time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent creates computational models that replicate and simulate RNA-protein interaction mechanisms, allowing virtual experimentation to replace costly and time-consuming physical experiments. The model copies the essential interaction dynamics through sequence feature extraction and prediction algorithms, enabling rapid analysis without laboratory resources.

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent replaces experimental laboratory methods with computational algorithms and machine learning models. Instead of using physical experimentation to detect interactions, the system uses sequence-based computational prediction, substituting mechanical/experimental processes with information processing and mathematical modeling.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If experimental methods are used to study RNA-protein interactions, then interaction data can be obtained, but the process is expensive

Engineering Contradiction:
Improveinteraction data accuracyVSAvoidresearch cost
Core Design Contradiction:
Measurement precisionVSUse of energy by moving object

Solution Approach 1:

The patent creates computational models that replicate and simulate RNA-protein interaction mechanisms, allowing virtual experimentation to replace costly physical experiments. The model copies the essential interaction dynamics through sequence feature extraction and prediction algorithms, enabling rapid analysis without laboratory resources.

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent replaces experimental laboratory methods with computational algorithms and machine learning models. Instead of using physical experimentation to detect interactions, the system uses sequence-based computational prediction, substituting mechanical/experimental processes with information processing and mathematical modeling.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Measurement precision

If multiple interaction prediction models are used, then prediction accuracy is improved, but model complexity increases

Engineering Contradiction:
Improveprediction accuracyVSAvoidmodel complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines multiple interaction prediction models into a unified framework that processes sequence features through different computational approaches simultaneously. By merging these models, the system leverages the strengths of each algorithm while presenting a cohesive prediction interface, improving accuracy without proportionally increasing operational complexity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent develops a universal prediction system that can handle various RNA-protein interaction scenarios through a single integrated platform. The system universally processes different sequence types and interaction modes through common feature extraction and prediction mechanisms, reducing the need for separate specialized models for each interaction type.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS20250054571A1Method and apparatus for predicting RNA-protein interaction, medium and electronic device
Publication Date: 2025.02.13 BOE TECHNOLOGY GROUP CO LTD
  • US20250054571A1 patent drawing
  • US20250054571A1 patent drawing
  • US20250054571A1 patent drawing

AI summary

A method for predicting an RNA-protein interaction, relates to the technical field of artificial intelligence. The method includes: acquiring an RNA-protein pair to be predicted; obtaining a sequence feature of the RNA-protein pair to be predicted by performing feature extraction on the RNA-protein pair to be predicted; obtaining an RNA sequence representation vector and a protein sequence representation vector in the RNA-protein pair to be predicted by vectorizing the RNA-protein pair to be predicted; obtaining respectively by using multiple interaction prediction models, multiple interaction prediction values of the RNA-protein pair to be predicted, based on the sequence feature of the RNA-protein pair to be predicted, the RNA sequence representation vector and the protein sequence representation vector in the RNA-protein pair to be predicted; and determining an interaction between the RNA and the protein according to the multiple interaction prediction values.